Glossary
What is LOD and LOQ?
The limit of detection (LOD) is the lowest amount of an analyte that a method can reliably detect. The limit of quantitation (LOQ) is the lowest amount it can measure with acceptable precision and accuracy. Under ICH Q2, they are often estimated from signal-to-noise ratios of about 3:1 and 10:1 respectively, or from the standard deviation of the response and the calibration slope.