1-(2-Pyrimidyl)piperazine Dihydrochloride

Name: 1-(2-Pyrimidyl)piperazine Dihydrochloride
Brand: Vaqora Chemicals
SKU: VQ-043855

About 1-(2-Pyrimidyl)piperazine Dihydrochloride

1-(2-Pyrimidyl)piperazine Dihydrochloride is a metabolite or degradation product of Buspirone carrying the CAS registry number 94021-22-4. The compound has the formula C8H14Cl2N4, corresponding to a molecular weight of 237.13 g/mol. Alternative names: 2-Piperazinylpyrimidine dihydrochloride and 2-Piperazinylpyrimidine HCl.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Buspirone, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 1-(2-Pyrimidyl)piperazine Dihydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Buspirone

View every impurity, metabolite and intermediate we list for Buspirone.

Buspirone impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(2-Pyrimidyl)piperazine Dihydrochloride
Catalogue No.	VQ-043855
CAS Number	94021-22-4
IUPAC name	2-piperazin-1-ylpyrimidine;dihydrochloride
Molecular formula	C₈H₁₄Cl₂N₄
Molecular weight	237.13 g/mol
Exact mass	236.0596
Grade	Reference Standard
HSN code	38229090
InChIKey	ZNZGJSLHXOMREP-UHFFFAOYSA-N
SMILES	C1CN(CCN1)C2=NC=CC=N2.Cl.Cl
PubChem CID	11680272

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 4
TPSA	41.1 Å²
Synonyms	2-Piperazinylpyrimidine dihydrochloride, 2-Piperazinylpyrimidine HCl, 2-(1-Piperazinyl)pyrimidine dihydrochloride, 2-(Piperazin-1-yl)pyrimidine dihydrochloride, 1-(2-pyrimidinyl)piperazine dihydrochloride, 2-piperazin-1-ylpyrimidine Dihydrochloride, Pyrimidine, 2-(1-piperazinyl)-, dihydrochloride, N-(2-pyrimidinyl)piperazine dihydrochloride, 1-PP dihydrochloride, 2-(1-Piperazinyl)pyrimidineDihydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(2-Pyrimidyl)piperazine Dihydrochloride?

The CAS Registry Number of 1-(2-Pyrimidyl)piperazine Dihydrochloride is 94021-22-4. It is also known as 2-Piperazinylpyrimidine dihydrochloride, 2-Piperazinylpyrimidine HCl, 2-(1-Piperazinyl)pyrimidine dihydrochloride.

What is the molecular formula and molecular weight of 1-(2-Pyrimidyl)piperazine Dihydrochloride?

1-(2-Pyrimidyl)piperazine Dihydrochloride has the molecular formula C8H14Cl2N4 and a molecular weight of 237.13 g/mol.

What is 1-(2-Pyrimidyl)piperazine Dihydrochloride used for?

1-(2-Pyrimidyl)piperazine Dihydrochloride is supplied as a characterised reference material related to Buspirone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(2-Pyrimidyl)piperazine Dihydrochloride can I order?

We supply 1-(2-Pyrimidyl)piperazine Dihydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(2-Pyrimidyl)piperazine Dihydrochloride?

Yes. Every lot of 1-(2-Pyrimidyl)piperazine Dihydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(2-Pyrimidyl)piperazine Dihydrochloride be shipped internationally?

Yes. 1-(2-Pyrimidyl)piperazine Dihydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.