1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piper… 74852-62-3

Name: 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine
Brand: Vaqora Chemicals
SKU: VQ-035149

About 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine

1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine is an impurity of Itraconazole carrying the CAS registry number 74852-62-3. The compound has the formula C17H21N3O, corresponding to a molecular weight of 283.37 g/mol. Its systematic (IUPAC) name is 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline. It is also known as 4-(4-(4-Methoxyphenyl)piperazin-1-yl)aniline or 4-[4-(4-methoxyphenyl)-1-piperazinyl]aniline.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Itraconazole, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Itraconazole

View every impurity, metabolite and intermediate we list for Itraconazole.

Itraconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine
Catalogue No.	VQ-035149
CAS Number	74852-62-3
IUPAC name	4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline
Molecular formula	C₁₇H₂₁N₃O
Molecular weight	283.37 g/mol
Exact mass	283.1685
Grade	Reference Standard
HSN code	38229090
InChIKey	VXEGSRKPIUDPQT-UHFFFAOYSA-N
SMILES	COC1=CC=C(C=C1)N2CCN(CC2)C3=CC=C(C=C3)N
PubChem CID	154406

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	1 / 4
TPSA	41.7 Å²
Synonyms	4-(4-(4-Methoxyphenyl)piperazin-1-yl)aniline, Benzenamine, 4-(4-(4-methoxyphenyl)-1-piperazinyl)-, 4-(4-(4-Methoxyphenyl)-1-piperazinyl)benzenamine, 4-[4-(4-methoxyphenyl)-1-piperazinyl]benzenamine, Benzenamine, 4-[4-(4-methoxyphenyl)-1-piperazinyl]-, 4-[4-(4-methoxyphenyl)-1-piperazinyl]aniline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine?

The CAS Registry Number of 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine is 74852-62-3. It is also known as 4-(4-(4-Methoxyphenyl)piperazin-1-yl)aniline, Benzenamine, 4-(4-(4-methoxyphenyl)-1-piperazinyl)-, 4-(4-(4-Methoxyphenyl)-1-piperazinyl)benzenamine.

What is the molecular formula and molecular weight of 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine?

1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine has the molecular formula C17H21N3O and a molecular weight of 283.37 g/mol. Its IUPAC name is 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline.

What is 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine used for?

1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine is supplied as a characterised reference material related to Itraconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine can I order?

We supply 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine?

Yes. Every lot of 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine be shipped internationally?

Yes. 1-(4-Amino Phenyl) 4-(4-Methoxy Phenyl) Piperazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.