1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one 859199-06-7

Name: 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one
Brand: Vaqora Chemicals
SKU: VQ-048963

About 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one

Vaqora Chemicals supplies 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one, an impurity of Lotilaner registered under CAS number 859199-06-7. With the molecular formula C7H7BrOS, it has a molar mass of 219.1 g/mol. Its systematic (IUPAC) name is 1-(5-bromo-4-methylthiophen-2-yl)ethanone. Common synonyms include 1-(5-bromo-4-methyl-2-thienyl)ethanone and Ethanone,1-(5-bromo-4-methyl-2-thienyl)-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Lotilaner to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lotilaner

View every impurity, metabolite and intermediate we list for Lotilaner.

Lotilaner impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one
Catalogue No.	VQ-048963
CAS Number	859199-06-7
IUPAC name	1-(5-bromo-4-methylthiophen-2-yl)ethanone
Molecular formula	C₇H₇BrOS
Molecular weight	219.1 g/mol
Exact mass	217.9401
Grade	Reference Standard
HSN code	38229090
InChIKey	KQZYEQHMHCHZKP-UHFFFAOYSA-N
SMILES	CC1=C(SC(=C1)C(=O)C)Br
PubChem CID	45480353

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	0 / 2
TPSA	45.3 Å²
Synonyms	1-(5-bromo-4-methyl-2-thienyl)ethanone, Ethanone,1-(5-bromo-4-methyl-2-thienyl)-, 1-(5-bromo-4-methyl-thiophen-2-yl)-ethanone, 1-{5-bromo-4-methyl-thiophen-2-yl}-ethanone, Benzyl-2-nitro-o-tolyl ether, 2-cynao-5-aminobenzotrifluride, 1-(5-bromo-4-methyl-2-thiophenyl)ethanone, REF DUPL: 2-Acetyl-5-bromo-4-methylthiophene

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one?

The CAS Registry Number of 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one is 859199-06-7. It is also known as 1-(5-bromo-4-methyl-2-thienyl)ethanone, Ethanone,1-(5-bromo-4-methyl-2-thienyl)-, 1-(5-bromo-4-methyl-thiophen-2-yl)-ethanone.

What is the molecular formula and molecular weight of 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one?

1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one has the molecular formula C7H7BrOS and a molecular weight of 219.1 g/mol. Its IUPAC name is 1-(5-bromo-4-methylthiophen-2-yl)ethanone.

What is 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one used for?

1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one is supplied as a characterised reference material related to Lotilaner. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one can I order?

We supply 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one?

Yes. Every lot of 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one be shipped internationally?

Yes. 1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.