1-(6-Bromo-2-naphthalenyl)-2-chloroethanone 1228551-86-7

Name: 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone
Brand: Vaqora Chemicals
SKU: VQ-052212

About 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone

Listed under CAS 1228551-86-7, 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone is a process intermediate or related compound of Telaprevir available from Vaqora Chemicals. Formula C12H8BrClO, molecular weight 283.55 g/mol. The IUPAC name is 1-(6-bromonaphthalen-2-yl)-2-chloroethanone. Alternative names: 1-(6-Bromo-naphthalen-2-yl)-2-chloro-ethanone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Telaprevir, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Telaprevir

View every impurity, metabolite and intermediate we list for Telaprevir.

Telaprevir impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(6-Bromo-2-naphthalenyl)-2-chloroethanone
Catalogue No.	VQ-052212
CAS Number	1228551-86-7
IUPAC name	1-(6-bromonaphthalen-2-yl)-2-chloroethanone
Molecular formula	C₁₂H₈BrClO
Molecular weight	283.55 g/mol
Exact mass	281.9447
InChIKey	VPGPECRRZUJQEN-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=CC(=C2)Br)C=C1C(=O)CCl
PubChem CID	86670862

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	0 / 1
TPSA	17.1 Å²

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P261, P262, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone?

The CAS Registry Number of 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone is 1228551-86-7. It is also known as 1-(6-Bromonaphthalen-2-yl)-2-chloroethan-1-one, 1-(6-Bromo-naphthalen-2-yl)-2-chloro-ethanone, Ethanone, 1-(6-bromo-2-naphthalenyl)-2-chloro-.

What is the molecular formula and molecular weight of 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone?

1-(6-Bromo-2-naphthalenyl)-2-chloroethanone has the molecular formula C12H8BrClO and a molecular weight of 283.55 g/mol. Its IUPAC name is 1-(6-bromonaphthalen-2-yl)-2-chloroethanone.

What is 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone used for?

1-(6-Bromo-2-naphthalenyl)-2-chloroethanone is supplied as a characterised reference material related to Telaprevir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone can I order?

We supply 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone?

Yes. Every lot of 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone be shipped internationally?

Yes. 1-(6-Bromo-2-naphthalenyl)-2-chloroethanone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.