1-Benzo[1,3]dioxol-5-ylmethyl-piperazine

Name: 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine
Brand: Vaqora Chemicals
SKU: VQ-044784

About 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine

1-Benzo[1,3]dioxol-5-ylmethyl-piperazine is an impurity of Piribedil carrying the CAS registry number 32231-06-4. The compound has the formula C12H16N2O2, corresponding to a molecular weight of 220.27 g/mol. The IUPAC name is 1-(1,3-benzodioxol-5-ylmethyl)piperazine. Common synonyms include 1-Piperonylpiperazine and Piperazine, 1-(3,4-methylenedioxybenzyl)-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Piribedil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Piribedil

View every impurity, metabolite and intermediate we list for Piribedil.

Piribedil impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Benzo[1,3]dioxol-5-ylmethyl-piperazine
Catalogue No.	VQ-044784
CAS Number	32231-06-4
IUPAC name	1-(1,3-benzodioxol-5-ylmethyl)piperazine
Molecular formula	C₁₂H₁₆N₂O₂
Molecular weight	220.27 g/mol
Exact mass	220.1212
Grade	Reference Standard
HSN code	38229090
InChIKey	NBOOZXVYXHATOW-UHFFFAOYSA-N
SMILES	C1CN(CCN1)CC2=CC3=C(C=C2)OCO3
PubChem CID	94426

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	1 / 4
TPSA	33.7 Å²
Synonyms	1-Piperonylpiperazine, Piperazine, 1-(3,4-methylenedioxybenzyl)-, 1-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazine, 1-(3,4-Methylenedioxybenzyl)piperazine, Piperazine, 1-(1,3-benzodioxol-5-ylmethyl)-, methylenedioxybenzylpiperazine, 1-(1,3-Benzodioxol-5-yl-methyl)piperazine, 5-(piperazinylmethyl)-2H-benzo[d]1,3-dioxolene, 1-(3,4-Methylendioxybenzyl)piperazine, Piperonyl piperazine, 1-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P264 + P265, P271, P280, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P319, P321, P332 + P317, P337 + P317, P362 + P364, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine?

The CAS Registry Number of 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine is 32231-06-4. It is also known as 1-Piperonylpiperazine, Piperazine, 1-(3,4-methylenedioxybenzyl)-, 1-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazine.

What is the molecular formula and molecular weight of 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine?

1-Benzo[1,3]dioxol-5-ylmethyl-piperazine has the molecular formula C12H16N2O2 and a molecular weight of 220.27 g/mol. Its IUPAC name is 1-(1,3-benzodioxol-5-ylmethyl)piperazine.

What is 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine used for?

1-Benzo[1,3]dioxol-5-ylmethyl-piperazine is supplied as a characterised reference material related to Piribedil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine can I order?

We supply 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine?

Yes. Every lot of 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine be shipped internationally?

Yes. 1-Benzo[1,3]dioxol-5-ylmethyl-piperazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.