1-Boc-3-azetidinone

Name: 1-Boc-3-azetidinone
Brand: Vaqora Chemicals
SKU: VQ-040205

About 1-Boc-3-azetidinone

Vaqora Chemicals supplies 1-Boc-3-azetidinone, an API impurity reference standard registered under CAS number 398489-26-4. Formula C8H13NO3, molecular weight 171.19 g/mol. Its systematic (IUPAC) name is tert-butyl 3-oxoazetidine-1-carboxylate. It is also known as 1-(tert-Butoxycarbonyl)-3-azetidinone or N-Boc-3-oxoazetidine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of the parent drug substance, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	1-Boc-3-azetidinone
Catalogue No.	VQ-040205
CAS Number	398489-26-4
IUPAC name	tert-butyl 3-oxoazetidine-1-carboxylate
Molecular formula	C₈H₁₃NO₃
Molecular weight	171.19 g/mol
Exact mass	171.0895
Grade	Reference Standard
HSN code	38229090
InChIKey	VMKIXWAFFVLJCK-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)N1CC(=O)C1
PubChem CID	1519404

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	0 / 3
TPSA	46.6 Å²
Synonyms	1-(tert-Butoxycarbonyl)-3-azetidinone, N-Boc-3-oxoazetidine, 1-Azetidinecarboxylic acid, 3-oxo-, 1,1-dimethylethyl ester, 3-oxoazetidine-1-carboxylic acid tert-butyl ester, 1-Boc-azetidin-3-one, tert-butyl 3-oxoazetidinecarboxylate, N-Boc-3-azetidinone, 1-Boc-azetidine-3-one, tert-Butyl-3-oxoazetidine-1-carboxylate, tert-Butyl3-oxoazetidine-1-carboxylate, BOC-3-oxo-azetidine, 1-Boc-azetidin-3-on

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Boc-3-azetidinone?

The CAS Registry Number of 1-Boc-3-azetidinone is 398489-26-4. It is also known as 1-(tert-Butoxycarbonyl)-3-azetidinone, N-Boc-3-oxoazetidine, 1-Azetidinecarboxylic acid, 3-oxo-, 1,1-dimethylethyl ester.

What is the molecular formula and molecular weight of 1-Boc-3-azetidinone?

1-Boc-3-azetidinone has the molecular formula C8H13NO3 and a molecular weight of 171.19 g/mol. Its IUPAC name is tert-butyl 3-oxoazetidine-1-carboxylate.

Which grade and pack sizes of 1-Boc-3-azetidinone can I order?

We supply 1-Boc-3-azetidinone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Boc-3-azetidinone?

Yes. Every lot of 1-Boc-3-azetidinone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Boc-3-azetidinone be shipped internationally?

Yes. 1-Boc-3-azetidinone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.