1-Bromo-2-butyne

Name: 1-Bromo-2-butyne
Brand: Vaqora Chemicals
SKU: VQ-012854

About 1-Bromo-2-butyne

1-Bromo-2-butyne (CAS 3355-28-0) is a process intermediate or related compound of Linagliptin offered by Vaqora Chemicals at a purity of 99%. Formula C4H5Br, molecular weight 132.99 g/mol. Its systematic (IUPAC) name is 1-bromobut-2-yne. Alternative names: 1-(Bromomethyl)-2-methylacetylene and 2-Butyn-1-yl bromide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Linagliptin, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-Bromo-2-butyne in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Linagliptin

View every impurity, metabolite and intermediate we list for Linagliptin.

Linagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Bromo-2-butyne
Catalogue No.	VQ-012854
CAS Number	3355-28-0
IUPAC name	1-bromobut-2-yne
Molecular formula	C₄H₅Br
Molecular weight	132.99 g/mol
Exact mass	131.9575
Grade	Reference Standard
Purity / assay	99%
InChIKey	LNNXOEHOXSYWLD-UHFFFAOYSA-N
SMILES	CC#CCBr
PubChem CID	2756862

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 0
TPSA	0 Å²
Synonyms	1-(Bromomethyl)-2-methylacetylene, 2-Butyn-1-yl bromide, 2-Butynyl bromide, 4-Bromobut-2-yne, 2-Butyne, 1-bromo-, bromo-2-butyne, 1-bromo2-butyne, but-2-ynylbromide, l-bromo-2-butine, 1-bromo-2-butine, 4-bromo-2-butyne, but-2-ynyl bromide

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Signal word: Warning

Hazard statements

H226Flammable liquid and vapor
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P233, P240, P241, P242, P243, P261, P264, P264 + P265, P271, P280, P302 + P352, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403 + P233, P403 + P235, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 3355-28-0

1-Bromo-2-butyne, 98%

CAS: 3355-28-0
Formula: C₄H₅Br
MW: 132.99 g/mol

VQ-010352

Frequently asked questions

What is the CAS number of 1-Bromo-2-butyne?

The CAS Registry Number of 1-Bromo-2-butyne is 3355-28-0. It is also known as 1-(Bromomethyl)-2-methylacetylene, 2-Butyn-1-yl bromide, 2-Butynyl bromide.

What is the molecular formula and molecular weight of 1-Bromo-2-butyne?

1-Bromo-2-butyne has the molecular formula C4H5Br and a molecular weight of 132.99 g/mol. Its IUPAC name is 1-bromobut-2-yne.

What is 1-Bromo-2-butyne used for?

1-Bromo-2-butyne is supplied as a characterised reference material related to Linagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Bromo-2-butyne can I order?

We supply 1-Bromo-2-butyne in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Bromo-2-butyne?

Yes. Every lot of 1-Bromo-2-butyne is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Bromo-2-butyne be shipped internationally?

Yes. 1-Bromo-2-butyne is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.