1-Chloro-2-methyl-2-propanol

Name: 1-Chloro-2-methyl-2-propanol
Brand: Vaqora Chemicals
SKU: VQ-037952

About 1-Chloro-2-methyl-2-propanol

Listed under CAS 558-42-9, 1-Chloro-2-methyl-2-propanol is an impurity of N methylpyrrolidone available from Vaqora Chemicals. With the molecular formula C4H9ClO, it has a molar mass of 108.57 g/mol. Its systematic (IUPAC) name is 1-chloro-2-methylpropan-2-ol. Common synonyms include 1Chloro2methylpropan2ol and 2-Propanol, 1-chloro-2-methyl-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This N methylpyrrolidone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-Chloro-2-methyl-2-propanol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to N methylpyrrolidone

View every impurity, metabolite and intermediate we list for N methylpyrrolidone.

N methylpyrrolidone impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Chloro-2-methyl-2-propanol
Catalogue No.	VQ-037952
CAS Number	558-42-9
IUPAC name	1-chloro-2-methylpropan-2-ol
Molecular formula	C₄H₉ClO
Molecular weight	108.57 g/mol
Exact mass	108.0342
Grade	Reference Standard
HSN code	38229090
InChIKey	JNOZGFXJZQXOSU-UHFFFAOYSA-N
SMILES	CC(C)(CCl)O
PubChem CID	68409

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	1 / 1
TPSA	20.2 Å²
Synonyms	1Chloro2methylpropan2ol, 2-Propanol, 1-chloro-2-methyl-, 1-chloro-2-methyl-propan-2-ol, Chloro-tert-butanol, Chloro-tert-butyl alcohol, 1-Chloro-tert-butyl alcohol, 2-Chloro-tert-butyl Alcohol, 1-chloro-2-isobutanol, 1-Chlor-2-methylpropanol-2, 1-Chloro-2-methylpropanol-2, 1-chloro-2-methyl propan-2-ol, 1-chloro-2-hydroxy-2-methylpropane

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Signal word: Warning

Hazard statements

H226Flammable liquid and vapor
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P233, P240, P241, P242, P243, P261, P264, P264 + P265, P271, P280, P302 + P352, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403 + P233, P403 + P235, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Chloro-2-methyl-2-propanol?

The CAS Registry Number of 1-Chloro-2-methyl-2-propanol is 558-42-9. It is also known as 1Chloro2methylpropan2ol, 2-Propanol, 1-chloro-2-methyl-, 1-chloro-2-methyl-propan-2-ol.

What is the molecular formula and molecular weight of 1-Chloro-2-methyl-2-propanol?

1-Chloro-2-methyl-2-propanol has the molecular formula C4H9ClO and a molecular weight of 108.57 g/mol. Its IUPAC name is 1-chloro-2-methylpropan-2-ol.

What is 1-Chloro-2-methyl-2-propanol used for?

1-Chloro-2-methyl-2-propanol is supplied as a characterised reference material related to N methylpyrrolidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Chloro-2-methyl-2-propanol can I order?

We supply 1-Chloro-2-methyl-2-propanol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Chloro-2-methyl-2-propanol?

Yes. Every lot of 1-Chloro-2-methyl-2-propanol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Chloro-2-methyl-2-propanol be shipped internationally?

Yes. 1-Chloro-2-methyl-2-propanol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.