1-Chloro-3-(1-naphthoxy)-2-propanol

Name: 1-Chloro-3-(1-naphthoxy)-2-propanol
Brand: Vaqora Chemicals
SKU: VQ-033375

About 1-Chloro-3-(1-naphthoxy)-2-propanol

1-Chloro-3-(1-naphthoxy)-2-propanol (CAS 20133-93-1) is an impurity of Propranolol offered by Vaqora Chemicals. With the molecular formula C13H13ClO2, it has a molar mass of 236.69 g/mol. The IUPAC name is 1-chloro-3-naphthalen-1-yloxypropan-2-ol. Common synonyms include 1-Chloro-3-(1-naphthyloxy)-2-propanol and 1-Cl-3-NP.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Propranolol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 1-Chloro-3-(1-naphthoxy)-2-propanol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Propranolol

View every impurity, metabolite and intermediate we list for Propranolol.

Propranolol impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Chloro-3-(1-naphthoxy)-2-propanol
Catalogue No.	VQ-033375
CAS Number	20133-93-1
IUPAC name	1-chloro-3-naphthalen-1-yloxypropan-2-ol
Molecular formula	C₁₃H₁₃ClO₂
Molecular weight	236.69 g/mol
Exact mass	236.0604
Grade	Reference Standard
HSN code	38229090
InChIKey	ZVVJOJMCXYDDEW-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C=CC=C2OCC(CCl)O
PubChem CID	89276

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 2
TPSA	29.5 Å²
Synonyms	1-Chloro-3-(1-naphthyloxy)-2-propanol, 1-Cl-3-NP, 1-chloro-3-(naphthalen-1-yloxy)propan-2-ol, 2-Propanol, 1-chloro-3-(1-naphthalenyloxy)-, 1-Chloro-3-(1-naphthyloxy)propan-2-ol, 1-Chloro-3-(1-naphthalenyloxy)-2-propanol, 1-(alpha-NAPHTHOXY)-3-CHLORO-2-PROPANOL, 1-(1-Naphthyloxy)-3-chloro-2-propanol, 1-Chloro-3-naphthalen-1-yloxy-propan-2-ol, 1(Naphth-1-yloxy)-3-chlor-propan-2-ol, 3-(alpha-Naphthoxy)-1-chloropropan-2-ol, 1-(Naphth-1-yloxy)-3-chloro-propan-2-ol

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P263, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Chloro-3-(1-naphthoxy)-2-propanol?

The CAS Registry Number of 1-Chloro-3-(1-naphthoxy)-2-propanol is 20133-93-1. It is also known as 1-Chloro-3-(1-naphthyloxy)-2-propanol, 1-Cl-3-NP, 1-chloro-3-(naphthalen-1-yloxy)propan-2-ol.

What is the molecular formula and molecular weight of 1-Chloro-3-(1-naphthoxy)-2-propanol?

1-Chloro-3-(1-naphthoxy)-2-propanol has the molecular formula C13H13ClO2 and a molecular weight of 236.69 g/mol. Its IUPAC name is 1-chloro-3-naphthalen-1-yloxypropan-2-ol.

What is 1-Chloro-3-(1-naphthoxy)-2-propanol used for?

1-Chloro-3-(1-naphthoxy)-2-propanol is supplied as a characterised reference material related to Propranolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Chloro-3-(1-naphthoxy)-2-propanol can I order?

We supply 1-Chloro-3-(1-naphthoxy)-2-propanol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Chloro-3-(1-naphthoxy)-2-propanol?

Yes. Every lot of 1-Chloro-3-(1-naphthoxy)-2-propanol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Chloro-3-(1-naphthoxy)-2-propanol be shipped internationally?

Yes. 1-Chloro-3-(1-naphthoxy)-2-propanol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.