1-(Chloroacetyl)-D-prolinamide

Name: 1-(Chloroacetyl)-D-prolinamide
Brand: Vaqora Chemicals
SKU: VQ-034623

About 1-(Chloroacetyl)-D-prolinamide

1-(Chloroacetyl)-D-prolinamide (CAS 1211679-98-9) is an impurity of Vildagliptin offered by Vaqora Chemicals. Its molecular formula is C7H11ClN2O2 and its molecular weight is 190.63 g/mol. Its systematic (IUPAC) name is (2R)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide. Common synonyms include Vildagliptin Chloroacetyl Amide (R)-Isomer.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Vildagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-(Chloroacetyl)-D-prolinamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vildagliptin

View every impurity, metabolite and intermediate we list for Vildagliptin.

Vildagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(Chloroacetyl)-D-prolinamide
Catalogue No.	VQ-034623
CAS Number	1211679-98-9
IUPAC name	(2R)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide
Molecular formula	C₇H₁₁ClN₂O₂
Molecular weight	190.63 g/mol
Exact mass	190.0509
Grade	Reference Standard
HSN code	38229090
InChIKey	YKDRUBGIBPCRBH-RXMQYKEDSA-N
SMILES	C1C[C@@H](N(C1)C(=O)CCl)C(=O)N
PubChem CID	11063231

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.7
H-bond donors / acceptors	1 / 2
TPSA	63.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(Chloroacetyl)-D-prolinamide?

The CAS Registry Number of 1-(Chloroacetyl)-D-prolinamide is 1211679-98-9. It is also known as Vildagliptin Chloroacetyl Amide (R)-Isomer, (R)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide.

What is the molecular formula and molecular weight of 1-(Chloroacetyl)-D-prolinamide?

1-(Chloroacetyl)-D-prolinamide has the molecular formula C7H11ClN2O2 and a molecular weight of 190.63 g/mol. Its IUPAC name is (2R)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide.

What is 1-(Chloroacetyl)-D-prolinamide used for?

1-(Chloroacetyl)-D-prolinamide is supplied as a characterised reference material related to Vildagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(Chloroacetyl)-D-prolinamide can I order?

We supply 1-(Chloroacetyl)-D-prolinamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(Chloroacetyl)-D-prolinamide?

Yes. Every lot of 1-(Chloroacetyl)-D-prolinamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(Chloroacetyl)-D-prolinamide be shipped internationally?

Yes. We export 1-(Chloroacetyl)-D-prolinamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.