1-Methyl-3-phenylpiperazine

Name: 1-Methyl-3-phenylpiperazine
Brand: Vaqora Chemicals
SKU: VQ-026730

About 1-Methyl-3-phenylpiperazine

1-Methyl-3-phenylpiperazine (CAS 5271-27-2) is a process intermediate or related compound of Mirtazapine offered by Vaqora Chemicals. Formula C11H16N2, molecular weight 176.26 g/mol. It is also known as N-Methyl-3-phenyl piperazine or 1-methyl-3-phenyl-1-piperazine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Mirtazapine, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 1-Methyl-3-phenylpiperazine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Mirtazapine

View every impurity, metabolite and intermediate we list for Mirtazapine.

Mirtazapine impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Methyl-3-phenylpiperazine
Catalogue No.	VQ-026730
CAS Number	5271-27-2
IUPAC name	1-methyl-3-phenylpiperazine
Molecular formula	C₁₁H₁₆N₂
Molecular weight	176.26 g/mol
Exact mass	176.1313
HSN code	2933
InChIKey	IRMBVBDXXYXPEW-UHFFFAOYSA-N
SMILES	CN1CCNC(C1)C2=CC=CC=C2
PubChem CID	2760009

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	1 / 2
TPSA	15.3 Å²
Synonyms	N-Methyl-3-phenyl piperazine, 1-methyl-3-phenyl-1-piperazine, 1-n-methyl-3-phenyl-piperazine, 3-Phenyl-1-methylpiperazine, (+/-)-, dl-1-methyl-3-phenyl-piperazine

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P264, P264 + P265, P270, P273, P280, P301 + P317, P302 + P352, P305 + P354 + P338, P317, P321, P330, P332 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Methyl-3-phenylpiperazine?

The CAS Registry Number of 1-Methyl-3-phenylpiperazine is 5271-27-2. It is also known as N-Methyl-3-phenyl piperazine, 1-methyl-3-phenyl-1-piperazine, 1-n-methyl-3-phenyl-piperazine.

What is the molecular formula and molecular weight of 1-Methyl-3-phenylpiperazine?

1-Methyl-3-phenylpiperazine has the molecular formula C11H16N2 and a molecular weight of 176.26 g/mol. Its IUPAC name is 1-methyl-3-phenylpiperazine.

What is 1-Methyl-3-phenylpiperazine used for?

1-Methyl-3-phenylpiperazine is supplied as a characterised reference material related to Mirtazapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Methyl-3-phenylpiperazine can I order?

We supply 1-Methyl-3-phenylpiperazine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Methyl-3-phenylpiperazine?

Yes. Every lot of 1-Methyl-3-phenylpiperazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Methyl-3-phenylpiperazine be shipped internationally?

Yes. 1-Methyl-3-phenylpiperazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.