1-Methylguanosine

Name: 1-Methylguanosine
Brand: Vaqora Chemicals
SKU: VQ-036081

About 1-Methylguanosine

Listed under CAS 2140-65-0, 1-Methylguanosine is an impurity of Guanosine available from Vaqora Chemicals. Formula C11H15N5O5, molecular weight 297.27 g/mol. The IUPAC name is 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one. Common synonyms include N1-Methylguanosine and N-methylguanosine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Guanosine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 1-Methylguanosine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Guanosine

View every impurity, metabolite and intermediate we list for Guanosine.

Guanosine impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Methylguanosine
Catalogue No.	VQ-036081
CAS Number	2140-65-0
IUPAC name	2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one
Molecular formula	C₁₁H₁₅N₅O₅
Molecular weight	297.27 g/mol
Exact mass	297.1073
Grade	Reference Standard
HSN code	38229090
InChIKey	UTAIYTHAJQNQDW-KQYNXXCUSA-N
SMILES	CN1C(=O)C2=C(N=C1N)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
PubChem CID	96373

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.7
H-bond donors / acceptors	4 / 7
TPSA	146 Å²
Synonyms	N1-Methylguanosine, 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1-methylpurin-6-one, N-methylguanosine, N1-Methylxylo-guanosine, trmd protein, N1-Methyl-D-guanosine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Methylguanosine?

The CAS Registry Number of 1-Methylguanosine is 2140-65-0. It is also known as N1-Methylguanosine, 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1-methylpurin-6-one, N-methylguanosine.

What is the molecular formula and molecular weight of 1-Methylguanosine?

1-Methylguanosine has the molecular formula C11H15N5O5 and a molecular weight of 297.27 g/mol. Its IUPAC name is 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one.

What is 1-Methylguanosine used for?

1-Methylguanosine is supplied as a characterised reference material related to Guanosine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Methylguanosine can I order?

We supply 1-Methylguanosine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Methylguanosine?

Yes. Every lot of 1-Methylguanosine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Methylguanosine be shipped internationally?

Yes. 1-Methylguanosine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.