1-Nitroso-L-tryptophan

Name: 1-Nitroso-L-tryptophan
Brand: Vaqora Chemicals
SKU: VQ-028562

About 1-Nitroso-L-tryptophan

1-Nitroso-L-tryptophan (CAS 68807-89-6) is a nitrosamine impurity of Tryptophan offered by Vaqora Chemicals. The compound has the formula C11H11N3O3, corresponding to a molecular weight of 233.22 g/mol. The IUPAC name is (2S)-2-amino-3-(1-nitrosoindol-3-yl)propanoic acid. It is also known as N-Nitroso Tryptophan or L-Tryptophan, 1-nitroso-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-Nitroso-L-tryptophan in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Tryptophan

View every impurity, metabolite and intermediate we list for Tryptophan.

Tryptophan impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Nitroso-L-tryptophan
Catalogue No.	VQ-028562
CAS Number	68807-89-6
IUPAC name	(2S)-2-amino-3-(1-nitrosoindol-3-yl)propanoic acid
Molecular formula	C₁₁H₁₁N₃O₃
Molecular weight	233.22 g/mol
Exact mass	233.08
Grade	Reference Standard
HSN code	38229090
InChIKey	WBQJTPDOGLYTBE-VIFPVBQESA-N
SMILES	C1=CC=C2C(=C1)C(=CN2N=O)C[C@@H](C(=O)O)N
PubChem CID	71367300

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.5
H-bond donors / acceptors	2 / 5
TPSA	97.7 Å²
Synonyms	N-Nitroso Tryptophan, L-Tryptophan, 1-nitroso-, NO-tryptophan, NO-L-tryptophan, (2S)-2-amino-3-(1-nitroso-1H-indol-3-yl)propanoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Nitroso-L-tryptophan?

The CAS Registry Number of 1-Nitroso-L-tryptophan is 68807-89-6. It is also known as N-Nitroso Tryptophan, L-Tryptophan, 1-nitroso-, NO-tryptophan.

What is the molecular formula and molecular weight of 1-Nitroso-L-tryptophan?

1-Nitroso-L-tryptophan has the molecular formula C11H11N3O3 and a molecular weight of 233.22 g/mol. Its IUPAC name is (2S)-2-amino-3-(1-nitrosoindol-3-yl)propanoic acid.

What is 1-Nitroso-L-tryptophan used for?

1-Nitroso-L-tryptophan is supplied as a characterised reference material related to Tryptophan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Nitroso-L-tryptophan can I order?

We supply 1-Nitroso-L-tryptophan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Nitroso-L-tryptophan?

Yes. Every lot of 1-Nitroso-L-tryptophan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Nitroso-L-tryptophan be shipped internationally?

Yes. We export 1-Nitroso-L-tryptophan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.