1-Nitrosoazetidine-3-carboxylic acid

Name: 1-Nitrosoazetidine-3-carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-032926

About 1-Nitrosoazetidine-3-carboxylic acid

1-Nitrosoazetidine-3-carboxylic acid is a nitrosamine impurity of Azetidine carrying the CAS registry number 102624-97-5. Its molecular formula is C4H6N2O3 and its molecular weight is 130.1 g/mol. It is also known as 1-Nitroso-3-azetidinecarboxylic acid or 3-Azetidinecarboxylic acid, 1-nitroso-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Azetidine, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-Nitrosoazetidine-3-carboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Azetidine

View every impurity, metabolite and intermediate we list for Azetidine.

Azetidine impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Nitrosoazetidine-3-carboxylic acid
Catalogue No.	VQ-032926
CAS Number	102624-97-5
IUPAC name	1-nitrosoazetidine-3-carboxylic acid
Molecular formula	C₄H₆N₂O₃
Molecular weight	130.1 g/mol
Exact mass	130.0378
Grade	Reference Standard
HSN code	38229090
InChIKey	LOKLKVWDANNUKQ-UHFFFAOYSA-N
SMILES	C1C(CN1N=O)C(=O)O
PubChem CID	20203577

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	1 / 5
TPSA	70 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Nitrosoazetidine-3-carboxylic acid?

The CAS Registry Number of 1-Nitrosoazetidine-3-carboxylic acid is 102624-97-5. It is also known as 1-Nitroso-3-azetidinecarboxylic acid, 3-Azetidinecarboxylic acid, 1-nitroso-.

What is the molecular formula and molecular weight of 1-Nitrosoazetidine-3-carboxylic acid?

1-Nitrosoazetidine-3-carboxylic acid has the molecular formula C4H6N2O3 and a molecular weight of 130.1 g/mol. Its IUPAC name is 1-nitrosoazetidine-3-carboxylic acid.

What is 1-Nitrosoazetidine-3-carboxylic acid used for?

1-Nitrosoazetidine-3-carboxylic acid is supplied as a characterised reference material related to Azetidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Nitrosoazetidine-3-carboxylic acid can I order?

We supply 1-Nitrosoazetidine-3-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Nitrosoazetidine-3-carboxylic acid?

Yes. Every lot of 1-Nitrosoazetidine-3-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Nitrosoazetidine-3-carboxylic acid be shipped internationally?

Yes. 1-Nitrosoazetidine-3-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.