1-p-(Tolyloxy)-2,3-epoxypropane

Name: 1-p-(Tolyloxy)-2,3-epoxypropane
Brand: Vaqora Chemicals
SKU: VQ-024609

About 1-p-(Tolyloxy)-2,3-epoxypropane

Vaqora Chemicals supplies 1-p-(Tolyloxy)-2,3-epoxypropane, an impurity of Bisoprolol registered under CAS number 2186-24-5. Its molecular formula is C10H12O2 and its molecular weight is 164.2 g/mol. The IUPAC name is 2-[(4-methylphenoxy)methyl]oxirane. Common synonyms include 2-((p-Tolyloxy)methyl)oxirane and Cresylglycide ether.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Bisoprolol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-p-(Tolyloxy)-2,3-epoxypropane in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bisoprolol

View every impurity, metabolite and intermediate we list for Bisoprolol.

Bisoprolol impurities

Specifications & identifiers

Chemical identifiers
Product name	1-p-(Tolyloxy)-2,3-epoxypropane
Catalogue No.	VQ-024609
CAS Number	2186-24-5
IUPAC name	2-[(4-methylphenoxy)methyl]oxirane
Molecular formula	C₁₀H₁₂O₂
Molecular weight	164.2 g/mol
Exact mass	164.0837
Grade	Reference Standard
HSN code	38229090
InChIKey	CUFXMPWHOWYNSO-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)OCC2CO2
PubChem CID	16606

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	0 / 2
TPSA	21.8 Å²
Synonyms	2-((p-Tolyloxy)methyl)oxirane, Cresylglycide ether, Tolyl glycidyl ether, Cresol glycidal ether, Cresol glycidyl ether, Glycidyl methylphenyl ether, Propane, 1,2-epoxy-3-(tolyloxy)-, p-Cresyl glycidyl ether, Glycidyl p-tolyl ether, p-Cresol glycidyl ether, 1,2-Epoxy-3-(p-tolyloxy)propane

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H341Suspected of causing genetic defects
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P272, P273, P280, P302 + P352, P318, P321, P332 + P317, P333 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-p-(Tolyloxy)-2,3-epoxypropane?

The CAS Registry Number of 1-p-(Tolyloxy)-2,3-epoxypropane is 2186-24-5. It is also known as 2-((p-Tolyloxy)methyl)oxirane, Cresylglycide ether, Tolyl glycidyl ether.

What is the molecular formula and molecular weight of 1-p-(Tolyloxy)-2,3-epoxypropane?

1-p-(Tolyloxy)-2,3-epoxypropane has the molecular formula C10H12O2 and a molecular weight of 164.2 g/mol. Its IUPAC name is 2-[(4-methylphenoxy)methyl]oxirane.

What is 1-p-(Tolyloxy)-2,3-epoxypropane used for?

1-p-(Tolyloxy)-2,3-epoxypropane is supplied as a characterised reference material related to Bisoprolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-p-(Tolyloxy)-2,3-epoxypropane can I order?

We supply 1-p-(Tolyloxy)-2,3-epoxypropane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-p-(Tolyloxy)-2,3-epoxypropane?

Yes. Every lot of 1-p-(Tolyloxy)-2,3-epoxypropane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-p-(Tolyloxy)-2,3-epoxypropane be shipped internationally?

Yes. 1-p-(Tolyloxy)-2,3-epoxypropane is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.