1-(Piperazin-1-yl)butan-1-one

Name: 1-(Piperazin-1-yl)butan-1-one
Brand: Vaqora Chemicals
SKU: VQ-012847

About 1-(Piperazin-1-yl)butan-1-one

Listed under CAS 18903-04-3, 1-(Piperazin-1-yl)butan-1-one is a process intermediate or related compound of Olaparib available from Vaqora Chemicals. Its molecular formula is C8H16N2O and its molecular weight is 156.23 g/mol. Common synonyms include 1-(1-Piperazinyl)-1-butanone and 1-(1-Oxobutyl)piperazine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Olaparib, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 1-(Piperazin-1-yl)butan-1-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Olaparib

View every impurity, metabolite and intermediate we list for Olaparib.

Olaparib impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(Piperazin-1-yl)butan-1-one
Catalogue No.	VQ-012847
CAS Number	18903-04-3
Other CAS	2503206-35-5
IUPAC name	1-piperazin-1-ylbutan-1-one
Molecular formula	C₈H₁₆N₂O
Molecular weight	156.23 g/mol
Exact mass	156.1263
Grade	Reference Standard
HSN code	2933
InChIKey	OGQQJMSDOICEAR-UHFFFAOYSA-N
SMILES	CCCC(=O)N1CCNCC1
PubChem CID	10749434

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	1 / 2
TPSA	32.3 Å²
Synonyms	1-(1-Piperazinyl)-1-butanone, 1-(1-Oxobutyl)piperazine, 1-Butyrylpiperazine, 1-n-Butyrylpiperazine, 1-Butanone, 1-(1-piperazinyl)-, Piperazine, 1-(1-oxobutyl)- (9CI), 4-(1-oxobutyl)-piperazine, Piperazine, 1-(1-oxobutyl)-

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P319, P321, P330, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(Piperazin-1-yl)butan-1-one?

The CAS Registry Number of 1-(Piperazin-1-yl)butan-1-one is 18903-04-3. It is also known as 1-(1-Piperazinyl)-1-butanone, 1-(1-Oxobutyl)piperazine, 1-Butyrylpiperazine.

What is the molecular formula and molecular weight of 1-(Piperazin-1-yl)butan-1-one?

1-(Piperazin-1-yl)butan-1-one has the molecular formula C8H16N2O and a molecular weight of 156.23 g/mol. Its IUPAC name is 1-piperazin-1-ylbutan-1-one.

What is 1-(Piperazin-1-yl)butan-1-one used for?

1-(Piperazin-1-yl)butan-1-one is supplied as a characterised reference material related to Olaparib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(Piperazin-1-yl)butan-1-one can I order?

We supply 1-(Piperazin-1-yl)butan-1-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(Piperazin-1-yl)butan-1-one?

Yes. Every lot of 1-(Piperazin-1-yl)butan-1-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(Piperazin-1-yl)butan-1-one be shipped internationally?

Yes. 1-(Piperazin-1-yl)butan-1-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.