10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thi… 59743-84-9

Name: 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one
Brand: Vaqora Chemicals
SKU: VQ-031391

About 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one

10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one (CAS 59743-84-9) is an impurity of Ketotifen offered by Vaqora Chemicals. The compound has the formula C14H10O2S, corresponding to a molecular weight of 242.29 g/mol. Its systematic (IUPAC) name is 8-methoxy-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-one. Common synonyms include Benzothiophen-10-methoxy-cycloheptanone and Benzo[b]thiophen-10-methoxycycloheptanone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Ketotifen, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ketotifen

View every impurity, metabolite and intermediate we list for Ketotifen.

Ketotifen impurities

Specifications & identifiers

Chemical identifiers
Product name	10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one
Catalogue No.	VQ-031391
CAS Number	59743-84-9
IUPAC name	8-methoxy-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-one
Molecular formula	C₁₄H₁₀O₂S
Molecular weight	242.29 g/mol
Exact mass	242.0402
Grade	Reference Standard
HSN code	38229090
InChIKey	ZSGIVIUNURDDJL-UHFFFAOYSA-N
SMILES	COC1=CC2=CC=CC=C2C(=O)C3=C1SC=C3
PubChem CID	2825162

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	0 / 3
TPSA	54.5 Å²
Synonyms	4H-Benzo[4,5]cyclohepta[1,2-b]thiophen-4-one, 10-methoxy-, 4H-Benzo(4,5)cyclohepta(1,2-b)thiophen-4-one, 10-methoxy-, Benzothiophen-10-methoxy-cycloheptanone, Benzo[b]thiophen-10-methoxycycloheptanone, 10-methoxy-4H-benzo[4,5]cyclohepta[b]thiophen-4-one, 8-methoxy-6-thiatricyclo[8.4.0.0^{3,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one?

The CAS Registry Number of 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one is 59743-84-9. It is also known as 4H-Benzo[4,5]cyclohepta[1,2-b]thiophen-4-one, 10-methoxy-, 4H-Benzo(4,5)cyclohepta(1,2-b)thiophen-4-one, 10-methoxy-, Benzothiophen-10-methoxy-cycloheptanone.

What is the molecular formula and molecular weight of 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one?

10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one has the molecular formula C14H10O2S and a molecular weight of 242.29 g/mol. Its IUPAC name is 8-methoxy-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-one.

What is 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one used for?

10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one is supplied as a characterised reference material related to Ketotifen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one can I order?

We supply 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one?

Yes. Every lot of 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one be shipped internationally?

Yes. 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2- b]thiophen-4-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.