1,1-Bis(methylthio)-2-nitroethylene

Name: 1,1-Bis(methylthio)-2-nitroethylene
Brand: Vaqora Chemicals
SKU: VQ-033454

About 1,1-Bis(methylthio)-2-nitroethylene

Listed under CAS 13623-94-4, 1,1-Bis(methylthio)-2-nitroethylene is a process intermediate or related compound of Ranitidine available from Vaqora Chemicals. With the molecular formula C4H7NO2S2, it has a molar mass of 165.2 g/mol. Its systematic (IUPAC) name is 1,1-bis(methylsulfanyl)-2-nitroethene. Alternative names: Bis(methylthio)-2-nitroethylene and 1-Nitro-2,2-bis(methylthio)ethylene.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Ranitidine, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Ranitidine

View every impurity, metabolite and intermediate we list for Ranitidine.

Ranitidine impurities

Specifications & identifiers

Chemical identifiers
Product name	1,1-Bis(methylthio)-2-nitroethylene
Catalogue No.	VQ-033454
CAS Number	13623-94-4
IUPAC name	1,1-bis(methylsulfanyl)-2-nitroethene
Molecular formula	C₄H₇NO₂S₂
Molecular weight	165.2 g/mol
Exact mass	164.9918
InChIKey	NXGHEDHQXXXTTP-UHFFFAOYSA-N
SMILES	CSC(=C[N+](=O)[O-])SC
PubChem CID	83623

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 4
TPSA	96.4 Å²
Synonyms	Bis(methylthio)-2-nitroethylene, Ranitidine intermediate (1,1-BIS(METHYLTHIO)-2-NITROETHYLENE), Ranitidine 1,1-Bis(methylthio)-2-nitroethylene, 1-Nitro-2,2-bis(methylthio)ethylene, Ethene, 1,1-bis(methylthio)-2-nitro-, Nitroketene dimethyl mercaptal, 1,1-bis(methylthio)-2-nitroethene, (2-nitroethene-1,1-diyl)bis(methylsulfane), 1,1-bis-(methylthio)-2-nitroethene, 1,1-dimethylthio-2-nitroethene

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,1-Bis(methylthio)-2-nitroethylene?

The CAS Registry Number of 1,1-Bis(methylthio)-2-nitroethylene is 13623-94-4. It is also known as Bis(methylthio)-2-nitroethylene, Ranitidine intermediate (1,1-BIS(METHYLTHIO)-2-NITROETHYLENE), Ranitidine 1,1-Bis(methylthio)-2-nitroethylene.

What is the molecular formula and molecular weight of 1,1-Bis(methylthio)-2-nitroethylene?

1,1-Bis(methylthio)-2-nitroethylene has the molecular formula C4H7NO2S2 and a molecular weight of 165.2 g/mol. Its IUPAC name is 1,1-bis(methylsulfanyl)-2-nitroethene.

What is 1,1-Bis(methylthio)-2-nitroethylene used for?

1,1-Bis(methylthio)-2-nitroethylene is supplied as a characterised reference material related to Ranitidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,1-Bis(methylthio)-2-nitroethylene can I order?

We supply 1,1-Bis(methylthio)-2-nitroethylene, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,1-Bis(methylthio)-2-nitroethylene?

Yes. Every lot of 1,1-Bis(methylthio)-2-nitroethylene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,1-Bis(methylthio)-2-nitroethylene be shipped internationally?

Yes. 1,1-Bis(methylthio)-2-nitroethylene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.