11-Hydroxy-N-methyl Dihydro Loratadine

Name: 11-Hydroxy-N-methyl Dihydro Loratadine
Brand: Vaqora Chemicals
SKU: VQ-031625

About 11-Hydroxy-N-methyl Dihydro Loratadine

Listed under CAS 38089-93-9, 11-Hydroxy-N-methyl Dihydro Loratadine is a metabolite or degradation product of Loratadine available from Vaqora Chemicals. With the molecular formula C20H23ClN2O, it has a molar mass of 342.9 g/mol. Systematically, it is named 13-chloro-2-(1-methylpiperidin-4-yl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ol. It is also known as 11-Hydroxy-N-methyldesloratadine or Desloratadine 11-hydroxy-N-methyl.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Loratadine, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 11-Hydroxy-N-methyl Dihydro Loratadine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Loratadine

View every impurity, metabolite and intermediate we list for Loratadine.

Loratadine impurities

Specifications & identifiers

Chemical identifiers
Product name	11-Hydroxy-N-methyl Dihydro Loratadine
Catalogue No.	VQ-031625
CAS Number	38089-93-9
IUPAC name	13-chloro-2-(1-methylpiperidin-4-yl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ol
Molecular formula	C₂₀H₂₃ClN₂O
Molecular weight	342.9 g/mol
Exact mass	342.1499
Grade	Reference Standard
HSN code	38229090
InChIKey	HSLLZISLOQPUNP-UHFFFAOYSA-N
SMILES	CN1CCC(CC1)C2(C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)O
PubChem CID	11961794

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 3
TPSA	36.4 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 11-Hydroxy-N-methyl Dihydro Loratadine?

The CAS Registry Number of 11-Hydroxy-N-methyl Dihydro Loratadine is 38089-93-9. It is also known as 11-Hydroxy-N-methyldesloratadine, Desloratadine 11-hydroxy-N-methyl, (+/-)-11-Hydroxy-N-methyldesloratadine.

What is the molecular formula and molecular weight of 11-Hydroxy-N-methyl Dihydro Loratadine?

11-Hydroxy-N-methyl Dihydro Loratadine has the molecular formula C20H23ClN2O and a molecular weight of 342.9 g/mol. Its IUPAC name is 13-chloro-2-(1-methylpiperidin-4-yl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ol.

What is 11-Hydroxy-N-methyl Dihydro Loratadine used for?

11-Hydroxy-N-methyl Dihydro Loratadine is supplied as a characterised reference material related to Loratadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 11-Hydroxy-N-methyl Dihydro Loratadine can I order?

We supply 11-Hydroxy-N-methyl Dihydro Loratadine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 11-Hydroxy-N-methyl Dihydro Loratadine?

Yes. Every lot of 11-Hydroxy-N-methyl Dihydro Loratadine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 11-Hydroxy-N-methyl Dihydro Loratadine be shipped internationally?

Yes. 11-Hydroxy-N-methyl Dihydro Loratadine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.