[12-20]-Bivalirudin

Name: [12-20]-Bivalirudin
Brand: Vaqora Chemicals
SKU: VQ-044688

About [12-20]-Bivalirudin

Vaqora Chemicals supplies [12-20]-Bivalirudin, an impurity of Bivalirudin registered under CAS number 1224964-34-4. Formula C55H74N16O14, molecular weight 1183.3 g/mol. Alternative names: 10-Gly-LHRH and 10-Glycine-LHRH.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Bivalirudin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bivalirudin

View every impurity, metabolite and intermediate we list for Bivalirudin.

Bivalirudin impurities

Specifications & identifiers

Chemical identifiers
Product name	[12-20]-Bivalirudin
Catalogue No.	VQ-044688
CAS Number	1224964-34-4
IUPAC name	2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-3-hydroxy-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]acetic acid
Molecular formula	C₅₅H₇₄N₁₆O₁₄
Molecular weight	1183.3 g/mol
Exact mass	1182.557
Grade	Reference Standard
HSN code	38229090
InChIKey	IGACZQNUZMBGFX-AQJXLSMYSA-N
SMILES	CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)NC(=O)CNC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6
PubChem CID	3081473

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.8
H-bond donors / acceptors	16 / 16
TPSA	469 Å²
Synonyms	10-Gly-LHRH, 10-Glycine-LHRH, 10-Glyoh-LHRH, Gnrh, gly(10)-, LHRH, Glycine(10)-, LHRH, Glyoh(10)-, LHRH, Gly(10)-, LHRH (free acid), LHRH (free acid) trifluoroacetate salt, LH-RH, Free Acid, pE-HWSYGLRPG-OH, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H360May damage fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of [12-20]-Bivalirudin?

The CAS Registry Number of [12-20]-Bivalirudin is 1224964-34-4. It is also known as 10-Gly-LHRH, 10-Glycine-LHRH, 10-Glyoh-LHRH.

What is the molecular formula and molecular weight of [12-20]-Bivalirudin?

[12-20]-Bivalirudin has the molecular formula C55H74N16O14 and a molecular weight of 1183.3 g/mol.

What is [12-20]-Bivalirudin used for?

[12-20]-Bivalirudin is supplied as a characterised reference material related to Bivalirudin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of [12-20]-Bivalirudin can I order?

We supply [12-20]-Bivalirudin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with [12-20]-Bivalirudin?

Yes. Every lot of [12-20]-Bivalirudin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can [12-20]-Bivalirudin be shipped internationally?

Yes. [12-20]-Bivalirudin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.