1,2-alpha-Epoxy Exemestane

Name: 1,2-alpha-Epoxy Exemestane
Brand: Vaqora Chemicals
SKU: VQ-022619

About 1,2-alpha-Epoxy Exemestane

1,2-alpha-Epoxy Exemestane (CAS 159354-61-7) is an impurity of Exemestane offered by Vaqora Chemicals. Its molecular formula is C20H24O3 and its molecular weight is 312.4 g/mol. Common synonyms include 1,2-α-Epoxy Exemestane and 1,2-epoxy Exemestane.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Exemestane to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1,2-alpha-Epoxy Exemestane in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Exemestane

View every impurity, metabolite and intermediate we list for Exemestane.

Exemestane impurities

Specifications & identifiers

Chemical identifiers
Product name	1,2-alpha-Epoxy Exemestane
Catalogue No.	VQ-022619
CAS Number	159354-61-7
IUPAC name	(1S,2R,3R,5R,11R,12S,16S)-2,16-dimethyl-9-methylidene-4-oxapentacyclo[9.7.0.02,8.03,5.012,16]octadec-7-ene-6,15-dione
Molecular formula	C₂₀H₂₄O₃
Molecular weight	312.4 g/mol
Exact mass	312.1725
Grade	Reference Standard
HSN code	38229090
InChIKey	ACZFVFMOZUAEEW-XXWSGHEVSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC(=C)C4=CC(=O)[C@H]5[C@@H]([C@]34C)O5
PubChem CID	118730170

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	0 / 3
TPSA	46.7 Å²
Synonyms	1,2-α-Epoxy Exemestane, 1,2-epoxy Exemestane, Epoxy Exemestane, 1,2-alpha-, (1alpha,2alpha)-1,2-Epoxy-6-methyleneandrost-4-ene-3,17-dione, Androst-4-ene-3,17-dione, 1,2-epoxy-6-methylene-, (1, A,2, A)-, Androst-4-ene-3,17-dione, 1,2-epoxy-6-methylene-, (1alpha,2alpha)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,2-alpha-Epoxy Exemestane?

The CAS Registry Number of 1,2-alpha-Epoxy Exemestane is 159354-61-7. It is also known as 1,2-α-Epoxy Exemestane, 1,2-epoxy Exemestane, Epoxy Exemestane, 1,2-alpha-.

What is the molecular formula and molecular weight of 1,2-alpha-Epoxy Exemestane?

1,2-alpha-Epoxy Exemestane has the molecular formula C20H24O3 and a molecular weight of 312.4 g/mol. Its IUPAC name is (1S,2R,3R,5R,11R,12S,16S)-2,16-dimethyl-9-methylidene-4-oxapentacyclo[9.7.0.02,8.03,5.012,16]octadec-7-ene-6,15-dione.

What is 1,2-alpha-Epoxy Exemestane used for?

1,2-alpha-Epoxy Exemestane is supplied as a characterised reference material related to Exemestane. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,2-alpha-Epoxy Exemestane can I order?

We supply 1,2-alpha-Epoxy Exemestane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,2-alpha-Epoxy Exemestane?

Yes. Every lot of 1,2-alpha-Epoxy Exemestane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,2-alpha-Epoxy Exemestane be shipped internationally?

Yes. We export 1,2-alpha-Epoxy Exemestane worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.