1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol 1187190-70-0

Name: 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol
Brand: Vaqora Chemicals
SKU: VQ-036444

About 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol

1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol (CAS 1187190-70-0) is a metabolite or degradation product of Crisaborole offered by Vaqora Chemicals. Its molecular formula is C7H7BO3 and its molecular weight is 149.94 g/mol. The IUPAC name is 1-hydroxy-3H-2,1-benzoxaborol-5-ol. Common synonyms include Benzo[c][1,2]oxaborole-1,5(3H)-diol and 1,3-dihydro-2,1-benzoxaborole-1,5-diol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Crisaborole, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Crisaborole

View every impurity, metabolite and intermediate we list for Crisaborole.

Crisaborole impurities

Specifications & identifiers

Chemical identifiers
Product name	1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol
Catalogue No.	VQ-036444
CAS Number	1187190-70-0
IUPAC name	1-hydroxy-3H-2,1-benzoxaborol-5-ol
Molecular formula	C₇H₇BO₃
Molecular weight	149.94 g/mol
Exact mass	150.0488
Grade	Reference Standard
HSN code	38229090
InChIKey	GEQGETTVGJBBOI-UHFFFAOYSA-N
SMILES	B1(C2=C(CO1)C=C(C=C2)O)O
PubChem CID	57968699

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	49.7 Å²
Synonyms	Benzo[c][1,2]oxaborole-1,5(3H)-diol, 1,3-dihydro-2,1-benzoxaborole-1,5-diol, 2,1-Benzoxaborol-5-ol, 1,3-dihydro-1-hydroxy-, Benzo(C)(1,2)oxaborole-1,5(3H)-diol, Benzo(C)(1,2)oxabo, 2,1-Benzoxaborole-1,5(3H)-diol, 3H-benzo[c][1,2]oxaborole-1,5-diol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol?

The CAS Registry Number of 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is 1187190-70-0. It is also known as Benzo[c][1,2]oxaborole-1,5(3H)-diol, 1,3-dihydro-2,1-benzoxaborole-1,5-diol, 2,1-Benzoxaborol-5-ol, 1,3-dihydro-1-hydroxy-.

What is the molecular formula and molecular weight of 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol?

1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol has the molecular formula C7H7BO3 and a molecular weight of 149.94 g/mol. Its IUPAC name is 1-hydroxy-3H-2,1-benzoxaborol-5-ol.

What is 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol used for?

1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is supplied as a characterised reference material related to Crisaborole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol can I order?

We supply 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol?

Yes. Every lot of 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol be shipped internationally?

Yes. 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.