(1,3-Dioxolan-2-yl)methanol

Name: (1,3-Dioxolan-2-yl)methanol
Brand: Vaqora Chemicals
SKU: VQ-048095

About (1,3-Dioxolan-2-yl)methanol

(1,3-Dioxolan-2-yl)methanol (CAS 5694-68-8) is a process intermediate or related compound of Doxofylline offered by Vaqora Chemicals. Formula C4H8O3, molecular weight 104.1 g/mol. It is also known as 1,3-Dioxolane-2-methanol or 2-(Hydroxymethyl)-1,3-dioxolane.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Doxofylline, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Doxofylline

View every impurity, metabolite and intermediate we list for Doxofylline.

Doxofylline impurities

Specifications & identifiers

Chemical identifiers
Product name	(1,3-Dioxolan-2-yl)methanol
Catalogue No.	VQ-048095
CAS Number	5694-68-8
IUPAC name	1,3-dioxolan-2-ylmethanol
Molecular formula	C₄H₈O₃
Molecular weight	104.1 g/mol
Exact mass	104.0473
InChIKey	ZAGUSKAXELYWCE-UHFFFAOYSA-N
SMILES	C1COC(O1)CO
PubChem CID	294864

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.8
H-bond donors / acceptors	1 / 3
TPSA	38.7 Å²
Synonyms	1,3-Dioxolane-2-methanol, 2-(Hydroxymethyl)-1,3-dioxolane, Acetaldehyde, hydroxy-, cyclic 1,2-ethanediyl acetal, 1,3-dioxolan-2-ylmethan-1-ol, 1,3-Dioxane-2-methanol, 2-Hydroxymethyl-1,3-dioxolan, 2(Hydroxymethyl)-1,3-dioxolane, Hydroxyacetaldehyde Ethylene Acetal, 2-HydroxyMethyl-1,3-dioxolaneC4H8O3

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H227Combustible liquid
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1,3-Dioxolan-2-yl)methanol?

The CAS Registry Number of (1,3-Dioxolan-2-yl)methanol is 5694-68-8. It is also known as 1,3-Dioxolane-2-methanol, 2-(Hydroxymethyl)-1,3-dioxolane, Acetaldehyde, hydroxy-, cyclic 1,2-ethanediyl acetal.

What is the molecular formula and molecular weight of (1,3-Dioxolan-2-yl)methanol?

(1,3-Dioxolan-2-yl)methanol has the molecular formula C4H8O3 and a molecular weight of 104.1 g/mol. Its IUPAC name is 1,3-dioxolan-2-ylmethanol.

What is (1,3-Dioxolan-2-yl)methanol used for?

(1,3-Dioxolan-2-yl)methanol is supplied as a characterised reference material related to Doxofylline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1,3-Dioxolan-2-yl)methanol can I order?

We supply (1,3-Dioxolan-2-yl)methanol, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1,3-Dioxolan-2-yl)methanol?

Yes. Every lot of (1,3-Dioxolan-2-yl)methanol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1,3-Dioxolan-2-yl)methanol be shipped internationally?

Yes. (1,3-Dioxolan-2-yl)methanol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.