16-Keto 17-β-Estradiol

Name: 16-Keto 17-β-Estradiol
Brand: Vaqora Chemicals
SKU: VQ-025647

About 16-Keto 17-β-Estradiol

16-Keto 17-β-Estradiol (CAS 566-75-6) is an impurity of Estradiol offered by Vaqora Chemicals. Its molecular formula is C18H22O3 and its molecular weight is 286.4 g/mol. The IUPAC name is (8R,9S,13S,14S,17R)-3,17-dihydroxy-13-methyl-7,8,9,11,12,14,15,17-octahydro-6H-cyclopenta[a]phenanthren-16-one. Common synonyms include 16-Ketoestradiol and 16-Keto 17beta-Estradiol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

This Estradiol impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 16-Keto 17-β-Estradiol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	16-Keto 17-β-Estradiol
Catalogue No.	VQ-025647
CAS Number	566-75-6
IUPAC name	(8R,9S,13S,14S,17R)-3,17-dihydroxy-13-methyl-7,8,9,11,12,14,15,17-octahydro-6H-cyclopenta[a]phenanthren-16-one
Molecular formula	C₁₈H₂₂O₃
Molecular weight	286.4 g/mol
Exact mass	286.1569
Grade	Reference Standard
HSN code	38229090
InChIKey	KJDGFQJCHFJTRH-YONAWACDSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CC(=O)[C@@H]2O)CCC4=C3C=CC(=C4)O
PubChem CID	66417

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	16-Ketoestradiol, 16-Keto 17beta-Estradiol, 16-Oxoestradiol, Estra-1,3,5(10)-trien-16-one, 3,17-dihydroxy-, (17beta)-, (17beta)-3,17-dihydroxyestra-1,3,5(10)-trien-16-one, estra-1,3,5(10)-triene-3 beta-,17 beta-diol-16-one, Estra-1,3,5(10)-trien-16-one, 3,17-dihydroxy-, (17.beta.)-, 16-Oxo-17beta-estradiol, 1,3,5(10)-Estratrien-3,17-beta-diol-16-one, 16-keto-estriol

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 16-Keto 17-β-Estradiol?

The CAS Registry Number of 16-Keto 17-β-Estradiol is 566-75-6. It is also known as 16-Ketoestradiol, 16-Keto 17beta-Estradiol, 16-Oxoestradiol.

What is the molecular formula and molecular weight of 16-Keto 17-β-Estradiol?

16-Keto 17-β-Estradiol has the molecular formula C18H22O3 and a molecular weight of 286.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,17R)-3,17-dihydroxy-13-methyl-7,8,9,11,12,14,15,17-octahydro-6H-cyclopenta[a]phenanthren-16-one.

What is 16-Keto 17-β-Estradiol used for?

16-Keto 17-β-Estradiol is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 16-Keto 17-β-Estradiol can I order?

We supply 16-Keto 17-β-Estradiol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 16-Keto 17-β-Estradiol?

Yes. Every lot of 16-Keto 17-β-Estradiol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 16-Keto 17-β-Estradiol be shipped internationally?

Yes. 16-Keto 17-β-Estradiol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.