17-Beta-Estradiol-16,16,17d3

Name: 17-Beta-Estradiol-16,16,17d3
Brand: Vaqora Chemicals
SKU: VQ-037134

About 17-Beta-Estradiol-16,16,17d3

Vaqora Chemicals supplies 17-Beta-Estradiol-16,16,17d3, a stable isotope labelled analogue related to Estradiol registered under CAS number 79037-37-9. The compound has the formula C18H24O2, corresponding to a molecular weight of 275.4 g/mol. Alternative names: TMIJ-0196 and Estradiol-[16,16,17-2H3].

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 17-Beta-Estradiol-16,16,17d3 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	17-Beta-Estradiol-16,16,17d3
Catalogue No.	VQ-037134
CAS Number	79037-37-9
IUPAC name	(8R,9S,13S,14S,17S)-16,16,17-trideuterio-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthrene-3,17-diol
Molecular formula	C₁₈H₂₄O₂
Molecular weight	275.4 g/mol
Exact mass	275.1965
Grade	Reference Standard
HSN code	38229090
InChIKey	VOXZDWNPVJITMN-SPGJGCHISA-N
SMILES	[2H][C@]1([C@]2(CC[C@H]3[C@H]([C@@H]2CC1([2H])[2H])CCC4=C3C=CC(=C4)O)C)O
PubChem CID	16213507

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H340May cause genetic defects
H350May cause cancer
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 17-Beta-Estradiol-16,16,17d3?

The CAS Registry Number of 17-Beta-Estradiol-16,16,17d3 is 79037-37-9. It is also known as TMIJ-0196, Estradiol-[16,16,17-2H3], (16,16,17-~2~H_3_)Estra-1,3,5(10)-triene-3,17beta-diol.

What is the molecular formula and molecular weight of 17-Beta-Estradiol-16,16,17d3?

17-Beta-Estradiol-16,16,17d3 has the molecular formula C18H24O2 and a molecular weight of 275.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,17S)-16,16,17-trideuterio-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthrene-3,17-diol.

What is 17-Beta-Estradiol-16,16,17d3 used for?

17-Beta-Estradiol-16,16,17d3 is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 17-Beta-Estradiol-16,16,17d3 can I order?

We supply 17-Beta-Estradiol-16,16,17d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 17-Beta-Estradiol-16,16,17d3?

Yes. Every lot of 17-Beta-Estradiol-16,16,17d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 17-Beta-Estradiol-16,16,17d3 be shipped internationally?

Yes. 17-Beta-Estradiol-16,16,17d3 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.