(1R,2R)-Cyclohexane-1,2-dicarboxylic acid

Name: (1R,2R)-Cyclohexane-1,2-dicarboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-031694

About (1R,2R)-Cyclohexane-1,2-dicarboxylic acid

Listed under CAS 46022-05-3, (1R,2R)-Cyclohexane-1,2-dicarboxylic acid is an impurity of Lurasidone available from Vaqora Chemicals. With the molecular formula C8H12O4, it has a molar mass of 172.18 g/mol. Its systematic (IUPAC) name is trans-(1R,2R)-cyclohexane-1,2-dicarboxylic acid. It is also known as (R,R)-1,2-Cyclohexanedicarboxylic Acid or (1R,2R)-1,2-Cyclohexanedicarboxylic Acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Lurasidone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (1R,2R)-Cyclohexane-1,2-dicarboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lurasidone

View every impurity, metabolite and intermediate we list for Lurasidone.

Lurasidone impurities

Specifications & identifiers

Chemical identifiers
Product name	(1R,2R)-Cyclohexane-1,2-dicarboxylic acid
Catalogue No.	VQ-031694
CAS Number	46022-05-3
IUPAC name	trans-(1R,2R)-cyclohexane-1,2-dicarboxylic acid
Molecular formula	C₈H₁₂O₄
Molecular weight	172.18 g/mol
Exact mass	172.0736
Grade	Reference Standard
HSN code	38229090
InChIKey	QSAWQNUELGIYBC-PHDIDXHHSA-N
SMILES	C1CC[C@H]([C@@H](C1)C(=O)O)C(=O)O
PubChem CID	720895

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	2 / 4
TPSA	74.6 Å²
Synonyms	(R,R)-1,2-Cyclohexanedicarboxylic Acid, (1R,2R)-1,2-Cyclohexanedicarboxylic Acid, trans-1,2-Cyclohexanedicarboxylic acid, Cyclohexane-1,2-dicarboxylic acid, trans-, 1,2-Cyclohexanedicarboxylic acid, trans-, Lurasidone INT 4, (1R-trans)-1,2-Cyclohexanedicarboxylic Acid, (-)-trans-1,2-Cyclohexanedicarboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1R,2R)-Cyclohexane-1,2-dicarboxylic acid?

The CAS Registry Number of (1R,2R)-Cyclohexane-1,2-dicarboxylic acid is 46022-05-3. It is also known as (R,R)-1,2-Cyclohexanedicarboxylic Acid, (1R,2R)-1,2-Cyclohexanedicarboxylic Acid, trans-1,2-Cyclohexanedicarboxylic acid.

What is the molecular formula and molecular weight of (1R,2R)-Cyclohexane-1,2-dicarboxylic acid?

(1R,2R)-Cyclohexane-1,2-dicarboxylic acid has the molecular formula C8H12O4 and a molecular weight of 172.18 g/mol. Its IUPAC name is trans-(1R,2R)-cyclohexane-1,2-dicarboxylic acid.

What is (1R,2R)-Cyclohexane-1,2-dicarboxylic acid used for?

(1R,2R)-Cyclohexane-1,2-dicarboxylic acid is supplied as a characterised reference material related to Lurasidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1R,2R)-Cyclohexane-1,2-dicarboxylic acid can I order?

We supply (1R,2R)-Cyclohexane-1,2-dicarboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1R,2R)-Cyclohexane-1,2-dicarboxylic acid?

Yes. Every lot of (1R,2R)-Cyclohexane-1,2-dicarboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1R,2R)-Cyclohexane-1,2-dicarboxylic acid be shipped internationally?

Yes. (1R,2R)-Cyclohexane-1,2-dicarboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.