(1R,2S)-(-)-Norephedrine hydrochloride

Name: (1R,2S)-(-)-Norephedrine hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-019837

About (1R,2S)-(-)-Norephedrine hydrochloride

(1R,2S)-(-)-Norephedrine hydrochloride (CAS 3198-15-0) is an impurity of Ephedrine offered by Vaqora Chemicals. Formula C9H14ClNO, molecular weight 187.66 g/mol. Common synonyms include L-Norephedrine Hcl and Propadrine hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Ephedrine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (1R,2S)-(-)-Norephedrine hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ephedrine

View every impurity, metabolite and intermediate we list for Ephedrine.

Ephedrine impurities

Specifications & identifiers

Chemical identifiers
Product name	(1R,2S)-(-)-Norephedrine hydrochloride
Catalogue No.	VQ-019837
CAS Number	3198-15-0
IUPAC name	(1R,2S)-2-amino-1-phenylpropan-1-ol;hydrochloride
Molecular formula	C₉H₁₄ClNO
Molecular weight	187.66 g/mol
Exact mass	187.0764
Grade	Reference Standard
HSN code	38229090
InChIKey	DYWNLSQWJMTVGJ-KUSKTZOESA-N
SMILES	C[C@@H]([C@@H](C1=CC=CC=C1)O)N.Cl
PubChem CID	62943

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 2
TPSA	46.3 Å²
Synonyms	L-Norephedrine Hcl, Propadrine hydrochloride, Hydriatine, Monydrin, Phenylpropanolamine HCl, Phenylaminopropanol hydrochloride, (+-)-Norephedrine hydrochloride, Norephedrine, hydrochloride, DL-1-Phenyl-2-amino-1-propanol monohydrochloride, (+-)-Phenylpropanolamine hydrochloride, dl-Norephedrine hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1R,2S)-(-)-Norephedrine hydrochloride?

The CAS Registry Number of (1R,2S)-(-)-Norephedrine hydrochloride is 3198-15-0. It is also known as L-Norephedrine Hcl, Propadrine hydrochloride, Hydriatine.

What is the molecular formula and molecular weight of (1R,2S)-(-)-Norephedrine hydrochloride?

(1R,2S)-(-)-Norephedrine hydrochloride has the molecular formula C9H14ClNO and a molecular weight of 187.66 g/mol.

What is (1R,2S)-(-)-Norephedrine hydrochloride used for?

(1R,2S)-(-)-Norephedrine hydrochloride is supplied as a characterised reference material related to Ephedrine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1R,2S)-(-)-Norephedrine hydrochloride can I order?

We supply (1R,2S)-(-)-Norephedrine hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1R,2S)-(-)-Norephedrine hydrochloride?

Yes. Every lot of (1R,2S)-(-)-Norephedrine hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1R,2S)-(-)-Norephedrine hydrochloride be shipped internationally?

Yes. (1R,2S)-(-)-Norephedrine hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.