(1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabic… 197142-36-2

Name: (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-042115

About (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid

Vaqora Chemicals supplies (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid, an impurity of Saxagliptin registered under CAS number 197142-36-2. Formula C11H17NO4, molecular weight 227.26 g/mol. The IUPAC name is (1S,3S,5S)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Saxagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Saxagliptin

View every impurity, metabolite and intermediate we list for Saxagliptin.

Saxagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
Catalogue No.	VQ-042115
CAS Number	197142-36-2
IUPAC name	(1S,3S,5S)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
Molecular formula	C₁₁H₁₇NO₄
Molecular weight	227.26 g/mol
Exact mass	227.1158
Grade	Reference Standard
HSN code	38229090
InChIKey	VXIIZQXOIDYWBS-FXQIFTODSA-N
SMILES	CC(C)(C)OC(=O)N1[C@H]2C[C@H]2C[C@H]1C(=O)O
PubChem CID	11138865

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	1 / 4
TPSA	66.8 Å²
Synonyms	2-(1,1-Dimethylethyl) (1S,3S,5S)-2-azabicyclo(3.1.0)hexane-2,3-dicarboxylate, 2-(1,1-Dimethylethyl) (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate, (1s,3s,5s)-2-boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid, 2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) ester, (1S,3S,5S)-, (1S,3S,5S)-2-aza-bicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid?

The CAS Registry Number of (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid is 197142-36-2. It is also known as 2-(1,1-Dimethylethyl) (1S,3S,5S)-2-azabicyclo(3.1.0)hexane-2,3-dicarboxylate, 2-(1,1-Dimethylethyl) (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate, (1s,3s,5s)-2-boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid.

What is the molecular formula and molecular weight of (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid?

(1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid has the molecular formula C11H17NO4 and a molecular weight of 227.26 g/mol. Its IUPAC name is (1S,3S,5S)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid.

What is (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid used for?

(1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid is supplied as a characterised reference material related to Saxagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid can I order?

We supply (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid?

Yes. Every lot of (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid be shipped internationally?

Yes. (1S,3S,5S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.