2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidaz… 2731008-04-9

Name: 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole
Brand: Vaqora Chemicals
SKU: VQ-024587

About 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole

2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole (CAS 2731008-04-9) is a nitrosamine impurity of Bilastine offered by Vaqora Chemicals. Formula C12H14N4O, molecular weight 230.27 g/mol. Its systematic (IUPAC) name is 2-(1-nitrosopiperidin-4-yl)-1H-benzimidazole. Alternative names: N1-Nitroso Bilastine and 2-(1-Nitroso-4-piperidinyl)-1H-benzimidazole.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Bilastine, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Bilastine

View every impurity, metabolite and intermediate we list for Bilastine.

Bilastine impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole
Catalogue No.	VQ-024587
CAS Number	2731008-04-9
IUPAC name	2-(1-nitrosopiperidin-4-yl)-1H-benzimidazole
Molecular formula	C₁₂H₁₄N₄O
Molecular weight	230.27 g/mol
Exact mass	230.1168
Grade	Reference Standard
HSN code	38229090
InChIKey	IHOBDEFDXZXTHP-UHFFFAOYSA-N
SMILES	C1CN(CCC1C2=NC3=CC=CC=C3N2)N=O
PubChem CID	165690044

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 4
TPSA	61.4 Å²

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole?

The CAS Registry Number of 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole is 2731008-04-9. It is also known as N1-Nitroso Bilastine, 2-(1-nitrosopiperidin-4-yl)-1H-1,3-benzodiazole, 2-(1-Nitroso-4-piperidinyl)-1H-benzimidazole.

What is the molecular formula and molecular weight of 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole?

2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole has the molecular formula C12H14N4O and a molecular weight of 230.27 g/mol. Its IUPAC name is 2-(1-nitrosopiperidin-4-yl)-1H-benzimidazole.

What is 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole used for?

2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole is supplied as a characterised reference material related to Bilastine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole can I order?

We supply 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole?

Yes. Every lot of 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole be shipped internationally?

Yes. 2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.