2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile 312307-38-3

Name: 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile
Brand: Vaqora Chemicals
SKU: VQ-034676

About 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile

Listed under CAS 312307-38-3, 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile is an impurity of Vonoprazan available from Vaqora Chemicals. Its molecular formula is C11H7FN2O and its molecular weight is 202.18 g/mol. Systematically, it is named 2-[2-(2-fluorophenyl)-2-oxoethyl]propanedinitrile. Common synonyms include 2-Malononitrilyl- 1-(2-fluorophenyl)ethanone and TAK-438( Vonoprazan fumarate) intermediate 1.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Vonoprazan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vonoprazan

View every impurity, metabolite and intermediate we list for Vonoprazan.

Vonoprazan impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile
Catalogue No.	VQ-034676
CAS Number	312307-38-3
IUPAC name	2-[2-(2-fluorophenyl)-2-oxoethyl]propanedinitrile
Molecular formula	C₁₁H₇FN₂O
Molecular weight	202.18 g/mol
Exact mass	202.0542
Grade	Reference Standard
HSN code	38229090
InChIKey	NOUFLZSMHQHSHA-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C(=O)CC(C#N)C#N)F
PubChem CID	86660270

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	0 / 4
TPSA	64.7 Å²
Synonyms	2-(2-(2-Fluorophenyl)-2-oxoethyl)propanedinitrile, [2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile, Propanedinitrile, 2-[2-(2-fluorophenyl)-2-oxoethyl]-, 2-Malononitrilyl- 1-(2-fluorophenyl)ethanone, TAK-438( Vonoprazan fumarate) intermediate 1, 2-[2-(2-fluorophenyl)-2-oxo-ethyl]propanedinitrile, Propanedinitrile,2-[2-(2-fluorophenyl)-2-oxoethyl]-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements: P261, P272, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile?

The CAS Registry Number of 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile is 312307-38-3. It is also known as 2-(2-(2-Fluorophenyl)-2-oxoethyl)propanedinitrile, [2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile, Propanedinitrile, 2-[2-(2-fluorophenyl)-2-oxoethyl]-.

What is the molecular formula and molecular weight of 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile?

2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile has the molecular formula C11H7FN2O and a molecular weight of 202.18 g/mol. Its IUPAC name is 2-[2-(2-fluorophenyl)-2-oxoethyl]propanedinitrile.

What is 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile used for?

2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile is supplied as a characterised reference material related to Vonoprazan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile can I order?

We supply 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile?

Yes. Every lot of 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile be shipped internationally?

Yes. 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.