2-(4-Nitrosopiperazin-1-yl)ethan-1-ol

Name: 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol
Brand: Vaqora Chemicals
SKU: VQ-021618

About 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol

Vaqora Chemicals supplies 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol, a nitrosamine impurity of Dasatinib registered under CAS number 48121-20-6. With the molecular formula C6H13N3O2, it has a molar mass of 159.19 g/mol. Its systematic (IUPAC) name is 2-(4-nitrosopiperazin-1-yl)ethanol. Common synonyms include 4-Nitrosopiperazine-1-ethanol and 2-(4-nitroso-piperazin-1-yl)-ethanol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Dasatinib, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Dasatinib

View every impurity, metabolite and intermediate we list for Dasatinib.

Dasatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(4-Nitrosopiperazin-1-yl)ethan-1-ol
Catalogue No.	VQ-021618
CAS Number	48121-20-6
IUPAC name	2-(4-nitrosopiperazin-1-yl)ethanol
Molecular formula	C₆H₁₃N₃O₂
Molecular weight	159.19 g/mol
Exact mass	159.1008
Grade	Reference Standard
HSN code	38229090
InChIKey	UGTGTQBGWNCKBI-UHFFFAOYSA-N
SMILES	C1CN(CCN1CCO)N=O
PubChem CID	12554626

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	1 / 5
TPSA	56.1 Å²
Synonyms	4-Nitrosopiperazine-1-ethanol, 2-(4-nitroso-piperazin-1-yl)-ethanol, 4-Nitroso-1-piperazineethanol, 2-(4-Nitroso-1-piperazinyl)ethanol, Nitroso 1(2-hydroxy ethyl)piperazine

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H332Harmful if inhaled
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements: P203, P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P318, P319, P321, P330, P362 + P364, P363, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol?

The CAS Registry Number of 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol is 48121-20-6. It is also known as 4-Nitrosopiperazine-1-ethanol, 2-(4-nitroso-piperazin-1-yl)-ethanol, 4-Nitroso-1-piperazineethanol.

What is the molecular formula and molecular weight of 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol?

2-(4-Nitrosopiperazin-1-yl)ethan-1-ol has the molecular formula C6H13N3O2 and a molecular weight of 159.19 g/mol. Its IUPAC name is 2-(4-nitrosopiperazin-1-yl)ethanol.

What is 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol used for?

2-(4-Nitrosopiperazin-1-yl)ethan-1-ol is supplied as a characterised reference material related to Dasatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol can I order?

We supply 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol?

Yes. Every lot of 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol be shipped internationally?

Yes. 2-(4-Nitrosopiperazin-1-yl)ethan-1-ol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.