2-Bromo-1-(4-chloro-phenyl)-propan-1-one

Name: 2-Bromo-1-(4-chloro-phenyl)-propan-1-one
Brand: Vaqora Chemicals
SKU: VQ-036049

About 2-Bromo-1-(4-chloro-phenyl)-propan-1-one

Vaqora Chemicals supplies 2-Bromo-1-(4-chloro-phenyl)-propan-1-one, an impurity of Bupropion registered under CAS number 877-37-2. With the molecular formula C9H8BrClO, it has a molar mass of 247.51 g/mol. It is also known as 2-bromo-1-(4-chlorophenyl)-1-propanone or 1-Propanone,2-bromo-1-(4-chlorophenyl)-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Bupropion to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Bromo-1-(4-chloro-phenyl)-propan-1-one in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Bromo-1-(4-chloro-phenyl)-propan-1-one
Catalogue No.	VQ-036049
CAS Number	877-37-2
IUPAC name	2-bromo-1-(4-chlorophenyl)propan-1-one
Molecular formula	C₉H₈BrClO
Molecular weight	247.51 g/mol
Exact mass	245.9447
Grade	Reference Standard
HSN code	38229090
InChIKey	SAKMPXRILWVZEG-UHFFFAOYSA-N
SMILES	CC(C(=O)C1=CC=C(C=C1)Cl)Br
PubChem CID	3788219

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	0 / 1
TPSA	17.1 Å²
Synonyms	2-bromo-1-(4-chlorophenyl)-1-propanone, 1-Propanone,2-bromo-1-(4-chlorophenyl)-, 2-bromo-4'-chloropropiophenone, 4'-chloro-2-bromopropiophenone, alpha-bromo-4'-chloropropiophenone, (4-chlorophenyl)-(1-bromoethyl)-ketone, 1-Propanone, 2-bromo-1-(4-chlorophenyl)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Bromo-1-(4-chloro-phenyl)-propan-1-one?

The CAS Registry Number of 2-Bromo-1-(4-chloro-phenyl)-propan-1-one is 877-37-2. It is also known as 2-bromo-1-(4-chlorophenyl)-1-propanone, 1-Propanone,2-bromo-1-(4-chlorophenyl)-, 2-bromo-4'-chloropropiophenone.

What is the molecular formula and molecular weight of 2-Bromo-1-(4-chloro-phenyl)-propan-1-one?

2-Bromo-1-(4-chloro-phenyl)-propan-1-one has the molecular formula C9H8BrClO and a molecular weight of 247.51 g/mol. Its IUPAC name is 2-bromo-1-(4-chlorophenyl)propan-1-one.

What is 2-Bromo-1-(4-chloro-phenyl)-propan-1-one used for?

2-Bromo-1-(4-chloro-phenyl)-propan-1-one is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Bromo-1-(4-chloro-phenyl)-propan-1-one can I order?

We supply 2-Bromo-1-(4-chloro-phenyl)-propan-1-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Bromo-1-(4-chloro-phenyl)-propan-1-one?

Yes. Every lot of 2-Bromo-1-(4-chloro-phenyl)-propan-1-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Bromo-1-(4-chloro-phenyl)-propan-1-one be shipped internationally?

Yes. 2-Bromo-1-(4-chloro-phenyl)-propan-1-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.