2-Chloro-1,3-propanediol

Name: 2-Chloro-1,3-propanediol
Brand: Vaqora Chemicals
SKU: VQ-049864

About 2-Chloro-1,3-propanediol

2-Chloro-1,3-propanediol (CAS 497-04-1) is a process intermediate or related compound of Allopurinol offered by Vaqora Chemicals. Its molecular formula is C3H7ClO2 and its molecular weight is 110.54 g/mol. Its systematic (IUPAC) name is 2-chloropropane-1,3-diol. It is also known as 1,3-Propanediol, 2-chloro- or Glycerol beta-chlorohydrin.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Allopurinol, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Allopurinol

View every impurity, metabolite and intermediate we list for Allopurinol.

Allopurinol impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-1,3-propanediol
Catalogue No.	VQ-049864
CAS Number	497-04-1
IUPAC name	2-chloropropane-1,3-diol
Molecular formula	C₃H₇ClO₂
Molecular weight	110.54 g/mol
Exact mass	110.0135
InChIKey	DYPJJAAKPQKWTM-UHFFFAOYSA-N
SMILES	C(C(CO)Cl)O
PubChem CID	10337

Physical properties
Physical form	Solid
LogP (XLogP3)	-1
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	1,3-Propanediol, 2-chloro-, Glycerol beta-chlorohydrin, 2-Chloro-1,3-dihydroxypropane, 2-MCPD, 2-Chloro-1,3-propandiol, 1,3-Propanediol,2-chloro-, 2-monochloropropanediol, 2-Monochloro-propanediol, 2-chloro-propane-1,3-diol

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-1,3-propanediol?

The CAS Registry Number of 2-Chloro-1,3-propanediol is 497-04-1. It is also known as 1,3-Propanediol, 2-chloro-, Glycerol beta-chlorohydrin, 2-Chloro-1,3-dihydroxypropane.

What is the molecular formula and molecular weight of 2-Chloro-1,3-propanediol?

2-Chloro-1,3-propanediol has the molecular formula C3H7ClO2 and a molecular weight of 110.54 g/mol. Its IUPAC name is 2-chloropropane-1,3-diol.

What is 2-Chloro-1,3-propanediol used for?

2-Chloro-1,3-propanediol is supplied as a characterised reference material related to Allopurinol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chloro-1,3-propanediol can I order?

We supply 2-Chloro-1,3-propanediol, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-1,3-propanediol?

Yes. Every lot of 2-Chloro-1,3-propanediol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-1,3-propanediol be shipped internationally?

Yes. 2-Chloro-1,3-propanediol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.