2-Chloro-2-bromoacetophenone

Name: 2-Chloro-2-bromoacetophenone
Brand: Vaqora Chemicals
SKU: VQ-032733

About 2-Chloro-2-bromoacetophenone

Vaqora Chemicals supplies 2-Chloro-2-bromoacetophenone, an impurity of Tulobuterol registered under CAS number 5000-66-8. With the molecular formula C8H6BrClO, it has a molar mass of 233.49 g/mol. Its systematic (IUPAC) name is 2-bromo-1-(2-chlorophenyl)ethanone. Common synonyms include 2-Bromo-1-(2-chlorophenyl)ethan-1-one and 2-Bromo-2′-Chloroacetophenone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Tulobuterol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tulobuterol

View every impurity, metabolite and intermediate we list for Tulobuterol.

Tulobuterol impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-2-bromoacetophenone
Catalogue No.	VQ-032733
CAS Number	5000-66-8
IUPAC name	2-bromo-1-(2-chlorophenyl)ethanone
Molecular formula	C₈H₆BrClO
Molecular weight	233.49 g/mol
Exact mass	231.9291
Grade	Reference Standard
HSN code	38229090
InChIKey	WZWWEVCLPKAQTA-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C(=O)CBr)Cl
PubChem CID	2735785

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 1
TPSA	17.1 Å²
Synonyms	2-Bromo-1-(2-chlorophenyl)ethan-1-one, 2-Bromo-2′-Chloroacetophenone, 2-Bromo-2'-chloroacetophenone, 2'-Chlorophenacyl bromide, 2-chlorophenacyl bromide, 2-chlorophenacylbromide, o-Chlorophenacyl bromide, 2-chloro phenacylbromide, Ethanone, 2-bromo-1-(2-chlorophenyl)-, 2-Bromo-2 inverted exclamation mark -chloroacetophenone, 2-Bromo-1-(2-chlorophenyl)-1-ethanone

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements: P260, P264, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-2-bromoacetophenone?

The CAS Registry Number of 2-Chloro-2-bromoacetophenone is 5000-66-8. It is also known as 2-Bromo-1-(2-chlorophenyl)ethan-1-one, 2-Bromo-2′-Chloroacetophenone, 2-Bromo-2'-chloroacetophenone.

What is the molecular formula and molecular weight of 2-Chloro-2-bromoacetophenone?

2-Chloro-2-bromoacetophenone has the molecular formula C8H6BrClO and a molecular weight of 233.49 g/mol. Its IUPAC name is 2-bromo-1-(2-chlorophenyl)ethanone.

What is 2-Chloro-2-bromoacetophenone used for?

2-Chloro-2-bromoacetophenone is supplied as a characterised reference material related to Tulobuterol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chloro-2-bromoacetophenone can I order?

We supply 2-Chloro-2-bromoacetophenone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-2-bromoacetophenone?

Yes. Every lot of 2-Chloro-2-bromoacetophenone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-2-bromoacetophenone be shipped internationally?

Yes. 2-Chloro-2-bromoacetophenone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.