2-Chloro-4′-fluoroacetophenone, 99%

Name: 2-Chloro-4′-fluoroacetophenone, 99%
Brand: Vaqora Chemicals
SKU: VQ-010560

About 2-Chloro-4′-fluoroacetophenone, 99%

Listed under CAS 456-04-2, 2-Chloro-4′-fluoroacetophenone is a fluorinated building block available from Vaqora Chemicals with a typical assay of 99%. The compound has the formula C8H6ClFO, corresponding to a molecular weight of 172.58 g/mol. The IUPAC name is 2-chloro-1-(4-fluorophenyl)ethanone. Common synonyms include ω-Chloro-4-fluoroacetophenone and 4-Fluorophenacyl chloride.

It is supplied as white to light yellow to light orange powder or crystals. Key physical data: a melting point of 47-50 °C. Store in a tightly closed container in a cool, dry and well-ventilated place. It carries the GHS signal word “Danger” with 9 hazard statements. Review the Safety Data Sheet before use.

Key uses span organic synthesis and API synthesis. Our customers for this product work in pharmaceutical manufacturing, academic and industrial research and agrochemical production.

Standard pack sizes are 5 g, 25 g and 100 g, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Organic synthesis
API synthesis

Industries

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-4′-fluoroacetophenone, 99%
Catalogue No.	VQ-010560
CAS Number	456-04-2
IUPAC name	2-chloro-1-(4-fluorophenyl)ethanone
Molecular formula	C₈H₆ClFO
Molecular weight	172.58 g/mol
Exact mass	172.0091
Purity / assay	99%
HSN code	29420090
InChIKey	UJZWJOQRSMOFMA-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(=O)CCl)F
PubChem CID	120248

Physical properties
Physical form	Crystalline
Appearance	White to light yellow to light orange powder or crystals
Melting point	47-50 °C
LogP (XLogP3)	2.3
H-bond donors / acceptors	0 / 2
TPSA	17.1 Å²
Synonyms	ω-Chloro-4-fluoroacetophenone, 4-Fluorophenacyl chloride, 2-Chloro-4'-fluoroacetophenone, p-Fluorophenacyl chloride, Ethanone, 2-chloro-1-(4-fluorophenyl)-, alpha-Chloro-4-fluoroacetophenone, Acetophenone, 2-chloro-4'-fluoro-, 2-Cl-4'-F-acetophenone, alpha-Chloro-p-fluoroacetophenone, 2-chloro-1-(4-fluorophenyl)ethan-1-one, 2'-chloro-4-fluoroacetophenone, 4-fluorophenacylchloride

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H330Fatal if inhaled
H335May cause respiratory irritation
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P261, P264, P264 + P265, P270, P271, P272, P273, P280, P284, P301 + P316, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P319, P320, P321, P330, P332 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-4′-fluoroacetophenone, 99%?

The CAS Registry Number of 2-Chloro-4′-fluoroacetophenone, 99% is 456-04-2. It is also known as ω-Chloro-4-fluoroacetophenone, 4-Fluorophenacyl chloride, 2-Chloro-4'-fluoroacetophenone.

What is the molecular formula and molecular weight of 2-Chloro-4′-fluoroacetophenone, 99%?

2-Chloro-4′-fluoroacetophenone, 99% has the molecular formula C8H6ClFO and a molecular weight of 172.58 g/mol. Its IUPAC name is 2-chloro-1-(4-fluorophenyl)ethanone.

Which grade and pack sizes of 2-Chloro-4′-fluoroacetophenone, 99% can I order?

We supply 2-Chloro-4′-fluoroacetophenone, 99% in (99%) grade, in 5 g, 25 g, 100 g packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-4′-fluoroacetophenone, 99%?

Yes. Every lot of 2-Chloro-4′-fluoroacetophenone, 99% is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-4′-fluoroacetophenone, 99% be shipped internationally?

Yes. 2-Chloro-4′-fluoroacetophenone, 99% is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.