2-Chloro-4-methoxyaniline

Name: 2-Chloro-4-methoxyaniline
Brand: Vaqora Chemicals
SKU: VQ-051375

About 2-Chloro-4-methoxyaniline

Vaqora Chemicals supplies 2-Chloro-4-methoxyaniline, a process intermediate or related compound of Lenvatinib registered under CAS number 29242-84-0. The compound has the formula C7H8ClNO, corresponding to a molecular weight of 157.6 g/mol. Common synonyms include 2-chloro-4-methoxyphenylamine and Benzenamine, 2-chloro-4-methoxy-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Lenvatinib, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Chloro-4-methoxyaniline in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Lenvatinib

View every impurity, metabolite and intermediate we list for Lenvatinib.

Lenvatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-4-methoxyaniline
Catalogue No.	VQ-051375
CAS Number	29242-84-0
IUPAC name	2-chloro-4-methoxyaniline
Molecular formula	C₇H₈ClNO
Molecular weight	157.6 g/mol
Exact mass	157.0294
HSN code	2933
InChIKey	LNEVUNYUJNORRV-UHFFFAOYSA-N
SMILES	COC1=CC(=C(C=C1)N)Cl
PubChem CID	407432

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 2
TPSA	35.3 Å²
Synonyms	2-chloro-4-methoxyphenylamine, Benzenamine, 2-chloro-4-methoxy-, 2-chloro-4-methoxybenzenamine, 3-Chloranisidin, 4-Methoxy-2-chloroaniline, 4-amino-3-chloroanisole, 2-Chloro-4-methoxy-phenylamine, Benzenamine,2-, 2-Chloro-p-anisidine, 3-chloro-4-anisidine, 2-Chloro-4-(methyloxy)aniline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-4-methoxyaniline?

The CAS Registry Number of 2-Chloro-4-methoxyaniline is 29242-84-0. It is also known as 2-chloro-4-methoxyphenylamine, Benzenamine, 2-chloro-4-methoxy-, 2-chloro-4-methoxybenzenamine.

What is the molecular formula and molecular weight of 2-Chloro-4-methoxyaniline?

2-Chloro-4-methoxyaniline has the molecular formula C7H8ClNO and a molecular weight of 157.6 g/mol. Its IUPAC name is 2-chloro-4-methoxyaniline.

What is 2-Chloro-4-methoxyaniline used for?

2-Chloro-4-methoxyaniline is supplied as a characterised reference material related to Lenvatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chloro-4-methoxyaniline can I order?

We supply 2-Chloro-4-methoxyaniline, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-4-methoxyaniline?

Yes. Every lot of 2-Chloro-4-methoxyaniline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-4-methoxyaniline be shipped internationally?

Yes. 2-Chloro-4-methoxyaniline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.