2-Chlorobenzotrifluoride

Name: 2-Chlorobenzotrifluoride
Brand: Vaqora Chemicals
SKU: VQ-026387

About 2-Chlorobenzotrifluoride

2-Chlorobenzotrifluoride is an impurity of Sorafenib carrying the CAS registry number 88-16-4. The compound has the formula C7H4ClF3, corresponding to a molecular weight of 180.55 g/mol. The IUPAC name is 1-chloro-2-(trifluoromethyl)benzene. It is also known as o-Chlorobenzotrifluoride or Chlorobenzotrifluoride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Sorafenib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 2-Chlorobenzotrifluoride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chlorobenzotrifluoride
Catalogue No.	VQ-026387
CAS Number	88-16-4
IUPAC name	1-chloro-2-(trifluoromethyl)benzene
Molecular formula	C₇H₄ClF₃
Molecular weight	180.55 g/mol
Exact mass	179.9954
Grade	Reference Standard
HSN code	38229090
InChIKey	DGRVQOKCSKDWIH-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C(F)(F)F)Cl
PubChem CID	6921

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	0 / 3
TPSA	0 Å²
Synonyms	o-Chlorobenzotrifluoride, Chlorobenzotrifluoride, 2-Chloro(trifluoromethyl)benzene, o-(Trifluoromethyl)chlorobenzene, Benzene, 1-chloro-2-(trifluoromethyl)-, 2-Chloro-alpha,alpha,alpha-trifluorotoluene, o-(Trifluoromethyl)phenyl chloride, o-Chloro-alpha,alpha,alpha-trifluorotoluene, Benzene, chloro(trifluoromethyl)-, Chlorotrifluorotoluene, (Trifluoromethyl)chlorobenzene, 2-trifluoromethylphenyl chloride

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Signal word: Warning

Hazard statements

H226Flammable liquid and vapor
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P233, P240, P241, P242, P243, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P370 + P378

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chlorobenzotrifluoride?

The CAS Registry Number of 2-Chlorobenzotrifluoride is 88-16-4. It is also known as o-Chlorobenzotrifluoride, Chlorobenzotrifluoride, 2-Chloro(trifluoromethyl)benzene.

What is the molecular formula and molecular weight of 2-Chlorobenzotrifluoride?

2-Chlorobenzotrifluoride has the molecular formula C7H4ClF3 and a molecular weight of 180.55 g/mol. Its IUPAC name is 1-chloro-2-(trifluoromethyl)benzene.

What is 2-Chlorobenzotrifluoride used for?

2-Chlorobenzotrifluoride is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chlorobenzotrifluoride can I order?

We supply 2-Chlorobenzotrifluoride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chlorobenzotrifluoride?

Yes. Every lot of 2-Chlorobenzotrifluoride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chlorobenzotrifluoride be shipped internationally?

Yes. 2-Chlorobenzotrifluoride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.