2-(Chloromethyl)-4-methylquinazoline 3-oxide

Name: 2-(Chloromethyl)-4-methylquinazoline 3-oxide
Brand: Vaqora Chemicals
SKU: VQ-031560

About 2-(Chloromethyl)-4-methylquinazoline 3-oxide

2-(Chloromethyl)-4-methylquinazoline 3-oxide (CAS 6640-59-1) is an impurity of Linagliptin offered by Vaqora Chemicals. With the molecular formula C10H9ClN2O, it has a molar mass of 208.64 g/mol. Systematically, it is named 2-(chloromethyl)-4-methyl-3-oxidoquinazolin-3-ium.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Linagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 2-(Chloromethyl)-4-methylquinazoline 3-oxide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Linagliptin

View every impurity, metabolite and intermediate we list for Linagliptin.

Linagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(Chloromethyl)-4-methylquinazoline 3-oxide
Catalogue No.	VQ-031560
CAS Number	6640-59-1
IUPAC name	2-(chloromethyl)-4-methyl-3-oxidoquinazolin-3-ium
Molecular formula	C₁₀H₉ClN₂O
Molecular weight	208.64 g/mol
Exact mass	208.0403
Grade	Reference Standard
HSN code	38229090
InChIKey	BUHMBFBOQCPBRM-UHFFFAOYSA-N
SMILES	CC1=[N+](C(=NC2=CC=CC=C12)CCl)[O-]
PubChem CID	493974

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	0 / 2
TPSA	38.4 Å²
Synonyms	2-(Chloromethyl)-4-methyl-2,3-dihydroquinazoline 3-oxide, 2-(Chloromethyl)-4-methylquinazolin-3-ium-3-olate, 2-(chloromethyl)-4-methyl-3-oxido-quinazolin-3-ium, Quinazoline, 2-(chloromethyl)-4-methyl-, 3-oxide, 2-(Chloromethyl)-4-methyl-3-oxo-3lambda~5~-quinazoline

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(Chloromethyl)-4-methylquinazoline 3-oxide?

The CAS Registry Number of 2-(Chloromethyl)-4-methylquinazoline 3-oxide is 6640-59-1. It is also known as 2-(Chloromethyl)-4-methyl-2,3-dihydroquinazoline 3-oxide, 2-(Chloromethyl)-4-methylquinazolin-3-ium-3-olate, 2-(chloromethyl)-4-methyl-3-oxido-quinazolin-3-ium.

What is the molecular formula and molecular weight of 2-(Chloromethyl)-4-methylquinazoline 3-oxide?

2-(Chloromethyl)-4-methylquinazoline 3-oxide has the molecular formula C10H9ClN2O and a molecular weight of 208.64 g/mol. Its IUPAC name is 2-(chloromethyl)-4-methyl-3-oxidoquinazolin-3-ium.

What is 2-(Chloromethyl)-4-methylquinazoline 3-oxide used for?

2-(Chloromethyl)-4-methylquinazoline 3-oxide is supplied as a characterised reference material related to Linagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(Chloromethyl)-4-methylquinazoline 3-oxide can I order?

We supply 2-(Chloromethyl)-4-methylquinazoline 3-oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(Chloromethyl)-4-methylquinazoline 3-oxide?

Yes. Every lot of 2-(Chloromethyl)-4-methylquinazoline 3-oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(Chloromethyl)-4-methylquinazoline 3-oxide be shipped internationally?

Yes. We export 2-(Chloromethyl)-4-methylquinazoline 3-oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.