2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Ch… 3601-89-6

Name: 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride
Brand: Vaqora Chemicals
SKU: VQ-032500

About 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride

Vaqora Chemicals supplies 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride, a process intermediate or related compound of Zidovudine registered under CAS number 3601-89-6. Its molecular formula is C21H21ClO5 and its molecular weight is 388.8 g/mol. Its systematic (IUPAC) name is [(2R,3S)-5-chloro-3-(4-methylbenzoyl)oxyoxolan-2-yl]methyl 4-methylbenzoate. Common synonyms include 1-Chloro-3,5-di-o-toluoyl-2-D-ribofuranose and Hoffer's chloro sugar.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Zidovudine, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Zidovudine

View every impurity, metabolite and intermediate we list for Zidovudine.

Zidovudine impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride
Catalogue No.	VQ-032500
CAS Number	3601-89-6
IUPAC name	[(2R,3S)-5-chloro-3-(4-methylbenzoyl)oxyoxolan-2-yl]methyl 4-methylbenzoate
Molecular formula	C₂₁H₂₁ClO₅
Molecular weight	388.8 g/mol
Exact mass	388.1078
InChIKey	FJHSYOMVMMNQJQ-PAMZHZACSA-N
SMILES	CC1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H](CC(O2)Cl)OC(=O)C3=CC=C(C=C3)C
PubChem CID	12907234

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	0 / 5
TPSA	61.8 Å²
Synonyms	1-Chloro-3,5-di-o-toluoyl-2-D-ribofuranose, 1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose, (2R,3S)-5-chloro-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate, 2-Deoxy-3,5-di-O-p-toluoyl-D-erythro-pentofuranosyl chloride, Hoffer's chloro sugar, 1-Chloro-2-deoxy-3,5-di-O-toluoyl-D-ribofuranose, CS-B0031, 1-chloro-3,5-ditoluyl-D-deoxyribose, D-erythro-Pentofuranosylchloride, 2-deoxy-, 3,5-bis(4-methylbenzoate), [(2R,3S)-5-chloro-3-(4-methylbenzoyl)oxy-tetrahydrofuran-2-yl]methyl 4-methylbenzoate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride?

The CAS Registry Number of 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride is 3601-89-6. It is also known as 1-Chloro-3,5-di-o-toluoyl-2-D-ribofuranose, 1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose, (2R,3S)-5-chloro-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate.

What is the molecular formula and molecular weight of 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride?

2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride has the molecular formula C21H21ClO5 and a molecular weight of 388.8 g/mol. Its IUPAC name is [(2R,3S)-5-chloro-3-(4-methylbenzoyl)oxyoxolan-2-yl]methyl 4-methylbenzoate.

What is 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride used for?

2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride is supplied as a characterised reference material related to Zidovudine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride can I order?

We supply 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride?

Yes. Every lot of 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride be shipped internationally?

Yes. 2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.