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Metabolites & Degradation ProductsReference StandardAvailable on request

2-Hydroxyibuprofen

Synonyms: Rac 2-Hydroxy Ibuprofen · Ibuprofen OH · 2,4'-(2-Hydroxy-2-methylpropyl)phenylpropionic acid · Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)-alpha-methyl-

CAS No.51146-55-5
FormulaC13H18O3
Mol. weight222.28
Catalogue No.VQ-031131
PurityReference Standard
HSN38229090

2-Hydroxyibuprofen (CAS 51146-55-5) – Ibuprofen impurity standard. C13H18O3, MW 222.28. From Vaqora Chemicals, with COA and worldwide delivery.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About 2-Hydroxyibuprofen

Vaqora Chemicals supplies 2-Hydroxyibuprofen, a metabolite or degradation product of Ibuprofen registered under CAS number 51146-55-5. The compound has the formula C13H18O3, corresponding to a molecular weight of 222.28 g/mol. Its systematic (IUPAC) name is 2-[4-(2-hydroxy-2-methylpropyl)phenyl]propanoic acid. Common synonyms include Rac 2-Hydroxy Ibuprofen and Ibuprofen OH.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Ibuprofen, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 2-Hydroxyibuprofen in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Industries

Related to Ibuprofen

View every impurity, metabolite and intermediate we list for Ibuprofen.

Ibuprofen impurities

Specifications & identifiers

Chemical identifiers
Product name2-Hydroxyibuprofen
Catalogue No.VQ-031131
CAS Number51146-55-5
IUPAC name2-[4-(2-hydroxy-2-methylpropyl)phenyl]propanoic acid
Molecular formulaC13H18O3
Molecular weight222.28 g/mol
Exact mass222.1256
GradeReference Standard
HSN code38229090
InChIKeyUJHKVYPPCJBOSG-UHFFFAOYSA-N
SMILESCC(C1=CC=C(C=C1)CC(C)(C)O)C(=O)O
PubChem CID10443535
Physical properties
Physical formSolid
LogP (XLogP3)2.1
H-bond donors / acceptors2 / 3
TPSA57.5 Ų
SynonymsRac 2-Hydroxy Ibuprofen, Ibuprofen OH, 2,4'-(2-Hydroxy-2-methylpropyl)phenylpropionic acid, Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)-alpha-methyl-, 2-(4-(2-Hydroxy-2-methylpropyl)phenyl)propanoic acid, 2-[4-(2-Hydroxy-2-methylpropyl)phenyl]propionic acid, Ibuprofen-2-hydroxy, 2-[4-(2-Hydroxy-2-methylpropyl)phenyl]propanoic Acid (2-Hydroxyibuprofen), 4-(2-hydroxy-2-methylpropyl)-alpha-methyl-benzeneacetic acid, Hydroxy-ibuprofen, 2-

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant

Signal word: Warning

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation
  • H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of 2-Hydroxyibuprofen?

The CAS Registry Number of 2-Hydroxyibuprofen is 51146-55-5. It is also known as Rac 2-Hydroxy Ibuprofen, Ibuprofen OH, 2,4'-(2-Hydroxy-2-methylpropyl)phenylpropionic acid.

What is the molecular formula and molecular weight of 2-Hydroxyibuprofen?

2-Hydroxyibuprofen has the molecular formula C13H18O3 and a molecular weight of 222.28 g/mol. Its IUPAC name is 2-[4-(2-hydroxy-2-methylpropyl)phenyl]propanoic acid.

What is 2-Hydroxyibuprofen used for?

2-Hydroxyibuprofen is supplied as a characterised reference material related to Ibuprofen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Hydroxyibuprofen can I order?

We supply 2-Hydroxyibuprofen in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Hydroxyibuprofen?

Yes. Every lot of 2-Hydroxyibuprofen is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Hydroxyibuprofen be shipped internationally?

Yes. 2-Hydroxyibuprofen is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about 2-Hydroxyibuprofen

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
How ordering works

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