2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol

Name: 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol
Brand: Vaqora Chemicals
SKU: VQ-025615

About 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol

Vaqora Chemicals supplies 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol, a metabolite or degradation product of Esomeprazole registered under CAS number 727375-13-5. Its molecular formula is C8H11NO2 and its molecular weight is 153.18 g/mol. Its systematic (IUPAC) name is 2-(hydroxymethyl)-3,5-dimethyl-1H-pyridin-4-one. It is also known as 4-Hydroxy-3,5-dimethyl-2-pyridinemethanol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Esomeprazole, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Esomeprazole

View every impurity, metabolite and intermediate we list for Esomeprazole.

Esomeprazole impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol
Catalogue No.	VQ-025615
CAS Number	727375-13-5
IUPAC name	2-(hydroxymethyl)-3,5-dimethyl-1H-pyridin-4-one
Molecular formula	C₈H₁₁NO₂
Molecular weight	153.18 g/mol
Exact mass	153.079
Grade	Reference Standard
HSN code	38229090
InChIKey	QAZJWGGYPDKWMQ-UHFFFAOYSA-N
SMILES	CC1=CNC(=C(C1=O)C)CO
PubChem CID	19347453

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	49.3 Å²
Synonyms	2-(Hydroxymethyl)-3,5-dimethylpyridin-4(1H)-one, 2-Pyridinemethanol, 4-hydroxy-3,5-dimethyl- (9CI), 4-Hydroxy-3,5-dimethyl-2-pyridinemethanol, 2-(Hydroxymethyl)-3,5-dimethyl-4(1H)-pyridinone, 6-(Hydroxymethyl)-3,5-dimethyl-4(3H)-pyridinone, 2-(hydroxymethyl)-3,5-dimethyl-1,4-dihydropyridin-4-one

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol?

The CAS Registry Number of 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol is 727375-13-5. It is also known as 2-(Hydroxymethyl)-3,5-dimethylpyridin-4(1H)-one, 2-Pyridinemethanol, 4-hydroxy-3,5-dimethyl- (9CI), 4-Hydroxy-3,5-dimethyl-2-pyridinemethanol.

What is the molecular formula and molecular weight of 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol?

2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol has the molecular formula C8H11NO2 and a molecular weight of 153.18 g/mol. Its IUPAC name is 2-(hydroxymethyl)-3,5-dimethyl-1H-pyridin-4-one.

What is 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol used for?

2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol is supplied as a characterised reference material related to Esomeprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol can I order?

We supply 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol?

Yes. Every lot of 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol be shipped internationally?

Yes. 2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.