2-Methoxy 17-β-Estradiol

Name: 2-Methoxy 17-β-Estradiol
Brand: Vaqora Chemicals
SKU: VQ-043164

About 2-Methoxy 17-β-Estradiol

Listed under CAS 362-07-2, 2-Methoxy 17-β-Estradiol is an impurity of Estradiol available from Vaqora Chemicals. With the molecular formula C19H26O3, it has a molar mass of 302.4 g/mol. The IUPAC name is (8R,9S,13S,14S,17S)-2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol. It is also known as 2-Methoxyestradiol or 2-Methoxyestradiol-17beta.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Estradiol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 2-Methoxy 17-β-Estradiol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Methoxy 17-β-Estradiol
Catalogue No.	VQ-043164
CAS Number	362-07-2
IUPAC name	(8R,9S,13S,14S,17S)-2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Molecular formula	C₁₉H₂₆O₃
Molecular weight	302.4 g/mol
Exact mass	302.1882
Grade	Reference Standard
HSN code	38229090
InChIKey	CQOQDQWUFQDJMK-SSTWWWIQSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=C(C=C34)OC)O
PubChem CID	66414

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	2 / 3
TPSA	49.7 Å²
Synonyms	2-Methoxyestradiol, 2-Methoxyestradiol-17beta, 2-ME2, 2-Hydroxyestradol 2-methyl ether, 2ME2, 2-methoxy-17beta-estradiol, 2-methoxyoestradiol, (17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol, 2-Methoxyestra-1,3,5(10)-triene-3,17beta-diol, Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-, 2-methoxy-estra-1,3,5(10)-triene-3,17beta-diol

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301+H311+H331Toxic if swallowed, in contact with skin or if inhaled
H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
H350May cause cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P262, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P318, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P391

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Methoxy 17-β-Estradiol?

The CAS Registry Number of 2-Methoxy 17-β-Estradiol is 362-07-2. It is also known as 2-Methoxyestradiol, 2-Methoxyestradiol-17beta, 2-ME2.

What is the molecular formula and molecular weight of 2-Methoxy 17-β-Estradiol?

2-Methoxy 17-β-Estradiol has the molecular formula C19H26O3 and a molecular weight of 302.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,17S)-2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol.

What is 2-Methoxy 17-β-Estradiol used for?

2-Methoxy 17-β-Estradiol is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Methoxy 17-β-Estradiol can I order?

We supply 2-Methoxy 17-β-Estradiol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Methoxy 17-β-Estradiol?

Yes. Every lot of 2-Methoxy 17-β-Estradiol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Methoxy 17-β-Estradiol be shipped internationally?

Yes. 2-Methoxy 17-β-Estradiol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.