2-Methoxy-5-nitrophenol

Name: 2-Methoxy-5-nitrophenol
Brand: Vaqora Chemicals
SKU: VQ-037563

About 2-Methoxy-5-nitrophenol

2-Methoxy-5-nitrophenol (CAS 636-93-1) is an impurity of Guaiacol offered by Vaqora Chemicals. With the molecular formula C7H7NO4, it has a molar mass of 169.13 g/mol. It is also known as 5-Nitro-2-Methoxy Phenol or 5-Nitroguaiacol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Guaiacol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Methoxy-5-nitrophenol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Guaiacol

View every impurity, metabolite and intermediate we list for Guaiacol.

Guaiacol impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Methoxy-5-nitrophenol
Catalogue No.	VQ-037563
CAS Number	636-93-1
IUPAC name	2-methoxy-5-nitrophenol
Molecular formula	C₇H₇NO₄
Molecular weight	169.13 g/mol
Exact mass	169.0375
Grade	Reference Standard
HSN code	38229090
InChIKey	KXKCTSZYNCDFFG-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C=C1)[N+](=O)[O-])O
PubChem CID	69471

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	1 / 4
TPSA	75.3 Å²
Synonyms	5-Nitro-2-Methoxy Phenol, 5-Nitroguaiacol, Phenol, 2-methoxy-5-nitro-, 3-Hydroxy-4-methoxynitrobenzene, 2-hydroxy-4-nitroanisole, 2-Methyloxy-5-nitrophenol, ghl.PD_Mitscher_leg0.1131, 2-Hydroxy-1-methoxy-4-nitrobenzene, CS-B1762, 3-Hydroxy-4-methoxy-1-nitrobenzene

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Methoxy-5-nitrophenol?

The CAS Registry Number of 2-Methoxy-5-nitrophenol is 636-93-1. It is also known as 5-Nitro-2-Methoxy Phenol, 5-Nitroguaiacol, Phenol, 2-methoxy-5-nitro-.

What is the molecular formula and molecular weight of 2-Methoxy-5-nitrophenol?

2-Methoxy-5-nitrophenol has the molecular formula C7H7NO4 and a molecular weight of 169.13 g/mol. Its IUPAC name is 2-methoxy-5-nitrophenol.

What is 2-Methoxy-5-nitrophenol used for?

2-Methoxy-5-nitrophenol is supplied as a characterised reference material related to Guaiacol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Methoxy-5-nitrophenol can I order?

We supply 2-Methoxy-5-nitrophenol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Methoxy-5-nitrophenol?

Yes. Every lot of 2-Methoxy-5-nitrophenol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Methoxy-5-nitrophenol be shipped internationally?

Yes. 2-Methoxy-5-nitrophenol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.