2-Methyl-5-nitrobenzoic acid

Name: 2-Methyl-5-nitrobenzoic acid
Brand: Vaqora Chemicals
SKU: VQ-037940

About 2-Methyl-5-nitrobenzoic acid

2-Methyl-5-nitrobenzoic acid is an impurity of Lenalidomide carrying the CAS registry number 1975-52-6. The compound has the formula C8H7NO4, corresponding to a molecular weight of 181.15 g/mol. Common synonyms include 5-Nitro-o-toluic acid and 3-Nitro-6-methylbenzoic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Lenalidomide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lenalidomide

View every impurity, metabolite and intermediate we list for Lenalidomide.

Lenalidomide impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Methyl-5-nitrobenzoic acid
Catalogue No.	VQ-037940
CAS Number	1975-52-6
IUPAC name	2-methyl-5-nitrobenzoic acid
Molecular formula	C₈H₇NO₄
Molecular weight	181.15 g/mol
Exact mass	181.0375
Grade	Reference Standard
HSN code	38229090
InChIKey	DJRFJAVPROZZFL-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)[N+](=O)[O-])C(=O)O
PubChem CID	519683

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 4
TPSA	83.1 Å²
Synonyms	5-Nitro-o-toluic acid, 3-Nitro-6-methylbenzoic acid, Benzoic acid, 2-methyl-5-nitro-, 5-nitro-2-methylbenzoic acid, o-Toluic acid, 5-nitro, 5-nitro-2-methyl-benzoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Methyl-5-nitrobenzoic acid?

The CAS Registry Number of 2-Methyl-5-nitrobenzoic acid is 1975-52-6. It is also known as 5-Nitro-o-toluic acid, 3-Nitro-6-methylbenzoic acid, Benzoic acid, 2-methyl-5-nitro-.

What is the molecular formula and molecular weight of 2-Methyl-5-nitrobenzoic acid?

2-Methyl-5-nitrobenzoic acid has the molecular formula C8H7NO4 and a molecular weight of 181.15 g/mol. Its IUPAC name is 2-methyl-5-nitrobenzoic acid.

What is 2-Methyl-5-nitrobenzoic acid used for?

2-Methyl-5-nitrobenzoic acid is supplied as a characterised reference material related to Lenalidomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Methyl-5-nitrobenzoic acid can I order?

We supply 2-Methyl-5-nitrobenzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Methyl-5-nitrobenzoic acid?

Yes. Every lot of 2-Methyl-5-nitrobenzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Methyl-5-nitrobenzoic acid be shipped internationally?

Yes. 2-Methyl-5-nitrobenzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.