2-Nitro-4-(trifluoromethyl)benzonitrile

Name: 2-Nitro-4-(trifluoromethyl)benzonitrile
Brand: Vaqora Chemicals
SKU: VQ-032187

About 2-Nitro-4-(trifluoromethyl)benzonitrile

Vaqora Chemicals supplies 2-Nitro-4-(trifluoromethyl)benzonitrile, an impurity of Nitisinone registered under CAS number 778-94-9. Its molecular formula is C8H3F3N2O2 and its molecular weight is 216.12 g/mol. Common synonyms include 4-Cyano-3-nitrobenzotrifluoride and Benzonitrile, 2-nitro-4-(trifluoromethyl)-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Nitisinone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Nitro-4-(trifluoromethyl)benzonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nitisinone

View every impurity, metabolite and intermediate we list for Nitisinone.

Nitisinone impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Nitro-4-(trifluoromethyl)benzonitrile
Catalogue No.	VQ-032187
CAS Number	778-94-9
IUPAC name	2-nitro-4-(trifluoromethyl)benzonitrile
Molecular formula	C₈H₃F₃N₂O₂
Molecular weight	216.12 g/mol
Exact mass	216.0147
Grade	Reference Standard
HSN code	38229090
InChIKey	BQCWLXXZTCLGSZ-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1C(F)(F)F)[N+](=O)[O-])C#N
PubChem CID	69902

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	0 / 6
TPSA	69.6 Å²

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Nitro-4-(trifluoromethyl)benzonitrile?

The CAS Registry Number of 2-Nitro-4-(trifluoromethyl)benzonitrile is 778-94-9. It is also known as 4-Cyano-3-nitrobenzotrifluoride, Benzonitrile, 2-nitro-4-(trifluoromethyl)-, 2-nitro-4-(trifluoromethyl)benzenecarbonitrile.

What is the molecular formula and molecular weight of 2-Nitro-4-(trifluoromethyl)benzonitrile?

2-Nitro-4-(trifluoromethyl)benzonitrile has the molecular formula C8H3F3N2O2 and a molecular weight of 216.12 g/mol. Its IUPAC name is 2-nitro-4-(trifluoromethyl)benzonitrile.

What is 2-Nitro-4-(trifluoromethyl)benzonitrile used for?

2-Nitro-4-(trifluoromethyl)benzonitrile is supplied as a characterised reference material related to Nitisinone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Nitro-4-(trifluoromethyl)benzonitrile can I order?

We supply 2-Nitro-4-(trifluoromethyl)benzonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Nitro-4-(trifluoromethyl)benzonitrile?

Yes. Every lot of 2-Nitro-4-(trifluoromethyl)benzonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Nitro-4-(trifluoromethyl)benzonitrile be shipped internationally?

Yes. 2-Nitro-4-(trifluoromethyl)benzonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.