2'-Nitro-4',5'-dimethoxyacetophenone

Name: 2'-Nitro-4',5'-dimethoxyacetophenone
Brand: Vaqora Chemicals
SKU: VQ-032752

About 2'-Nitro-4',5'-dimethoxyacetophenone

2'-Nitro-4',5'-dimethoxyacetophenone is an impurity of Tivozanib carrying the CAS registry number 4101-32-0. The compound has the formula C10H11NO5, corresponding to a molecular weight of 225.2 g/mol. Its systematic (IUPAC) name is 1-(4,5-dimethoxy-2-nitrophenyl)ethanone. Common synonyms include Ethanone, 1-(4,5-dimethoxy-2-nitrophenyl)- and 4',5'-dimethoxy-2'-nitroacetophenone.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Tivozanib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2'-Nitro-4',5'-dimethoxyacetophenone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tivozanib

View every impurity, metabolite and intermediate we list for Tivozanib.

Tivozanib impurities

Specifications & identifiers

Chemical identifiers
Product name	2'-Nitro-4',5'-dimethoxyacetophenone
Catalogue No.	VQ-032752
CAS Number	4101-32-0
IUPAC name	1-(4,5-dimethoxy-2-nitrophenyl)ethanone
Molecular formula	C₁₀H₁₁NO₅
Molecular weight	225.2 g/mol
Exact mass	225.0637
Grade	Reference Standard
HSN code	38229090
InChIKey	ZVLFGESHYMKNQP-UHFFFAOYSA-N
SMILES	CC(=O)C1=CC(=C(C=C1[N+](=O)[O-])OC)OC
PubChem CID	77737

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	0 / 5
TPSA	81.4 Å²
Synonyms	Ethanone, 1-(4,5-dimethoxy-2-nitrophenyl)-, 4',5'-dimethoxy-2'-nitroacetophenone, 1-(4,5-Dimethoxy-2-nitro-phenyl)-ethanone, 1-(4,5-dimethoxy-2-nitrophenyl)ethan-1-one, 3',4'-dimethoxy-6'-nitroacetophenone, 1-(4,5-dimethoxy-2-nitro-phenyl)ethanone, 1-(4,5-Dimethoxy-2-nitrophenyl)ethanone #, 1-(4,5-Dimethoxy-2-nitrophenyl)ethanone, AldrichCPR

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects

Precautionary statements: P203, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2'-Nitro-4',5'-dimethoxyacetophenone?

The CAS Registry Number of 2'-Nitro-4',5'-dimethoxyacetophenone is 4101-32-0. It is also known as Ethanone, 1-(4,5-dimethoxy-2-nitrophenyl)-, 4',5'-dimethoxy-2'-nitroacetophenone, 1-(4,5-Dimethoxy-2-nitro-phenyl)-ethanone.

What is the molecular formula and molecular weight of 2'-Nitro-4',5'-dimethoxyacetophenone?

2'-Nitro-4',5'-dimethoxyacetophenone has the molecular formula C10H11NO5 and a molecular weight of 225.2 g/mol. Its IUPAC name is 1-(4,5-dimethoxy-2-nitrophenyl)ethanone.

What is 2'-Nitro-4',5'-dimethoxyacetophenone used for?

2'-Nitro-4',5'-dimethoxyacetophenone is supplied as a characterised reference material related to Tivozanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2'-Nitro-4',5'-dimethoxyacetophenone can I order?

We supply 2'-Nitro-4',5'-dimethoxyacetophenone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2'-Nitro-4',5'-dimethoxyacetophenone?

Yes. Every lot of 2'-Nitro-4',5'-dimethoxyacetophenone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2'-Nitro-4',5'-dimethoxyacetophenone be shipped internationally?

Yes. 2'-Nitro-4',5'-dimethoxyacetophenone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.