2-Nitrobenzotrifluoride

Name: 2-Nitrobenzotrifluoride
Brand: Vaqora Chemicals
SKU: VQ-012967

About 2-Nitrobenzotrifluoride

Vaqora Chemicals supplies 2-Nitrobenzotrifluoride, a process intermediate or related compound of Enzalutamide registered under CAS number 384-22-5 at a purity of 99%. Formula C7H4F3NO2, molecular weight 191.11 g/mol. Systematically, it is named 1-nitro-2-(trifluoromethyl)benzene. Common synonyms include 2-(Trifluoromethyl)nitrobenzene and 2-Nitro-α,α,α-trifluorotoluene.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Enzalutamide, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Enzalutamide

View every impurity, metabolite and intermediate we list for Enzalutamide.

Enzalutamide impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Nitrobenzotrifluoride
Catalogue No.	VQ-012967
CAS Number	384-22-5
IUPAC name	1-nitro-2-(trifluoromethyl)benzene
Molecular formula	C₇H₄F₃NO₂
Molecular weight	191.11 g/mol
Exact mass	191.0194
Grade	Reference Standard
Purity / assay	99%
InChIKey	NDZJSUCUYPZXPR-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C(F)(F)F)[N+](=O)[O-]
PubChem CID	9795

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	0 / 5
TPSA	45.8 Å²
Synonyms	2-(Trifluoromethyl)nitrobenzene, 2-Nitro-α,α,α-trifluorotoluene, o-(Trifluoromethyl)nitrobenzene, o-Nitrobenzotrifluoride, α,α,α-Trifluoro-o-nitrotoluene, 2-Nitro-.alpha.,.alpha.,.alpha.-trifluorotoluene, Toluene, 2-nitro-.alpha.,.alpha.,.alpha.-trifluoro-, oNitrobenzotrifluoride, 2Nitrobenzotrifluoride, o(Trifluoromethyl)nitrobenzene, 1Nitro2(trifluoromethyl)benzene, 1-Nitro-2(trifluoromethyl)benzene

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301+H311+H331Toxic if swallowed, in contact with skin or if inhaled
H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H330Fatal if inhaled
H331Toxic if inhaled
H335May cause respiratory irritation

Precautionary statements: P260, P261, P262, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P319, P320, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Nitrobenzotrifluoride?

The CAS Registry Number of 2-Nitrobenzotrifluoride is 384-22-5. It is also known as 2-(Trifluoromethyl)nitrobenzene, 2-Nitro-α,α,α-trifluorotoluene, o-(Trifluoromethyl)nitrobenzene.

What is the molecular formula and molecular weight of 2-Nitrobenzotrifluoride?

2-Nitrobenzotrifluoride has the molecular formula C7H4F3NO2 and a molecular weight of 191.11 g/mol. Its IUPAC name is 1-nitro-2-(trifluoromethyl)benzene.

What is 2-Nitrobenzotrifluoride used for?

2-Nitrobenzotrifluoride is supplied as a characterised reference material related to Enzalutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Nitrobenzotrifluoride can I order?

We supply 2-Nitrobenzotrifluoride in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Nitrobenzotrifluoride?

Yes. Every lot of 2-Nitrobenzotrifluoride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Nitrobenzotrifluoride be shipped internationally?

Yes. 2-Nitrobenzotrifluoride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.