2-(Piperazin-1-yl)phenol

Name: 2-(Piperazin-1-yl)phenol
Brand: Vaqora Chemicals
SKU: VQ-032616

About 2-(Piperazin-1-yl)phenol

2-(Piperazin-1-yl)phenol is an impurity of Vortioxetine carrying the CAS registry number 1011-17-2. Formula C10H14N2O, molecular weight 178.23 g/mol. Common synonyms include 2-(1-piperazinyl)phenol and o-(1-Piperazinyl)phenol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Vortioxetine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 2-(Piperazin-1-yl)phenol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vortioxetine

View every impurity, metabolite and intermediate we list for Vortioxetine.

Vortioxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(Piperazin-1-yl)phenol
Catalogue No.	VQ-032616
CAS Number	1011-17-2
IUPAC name	2-piperazin-1-ylphenol
Molecular formula	C₁₀H₁₄N₂O
Molecular weight	178.23 g/mol
Exact mass	178.1106
Grade	Reference Standard
HSN code	38229090
InChIKey	UORNTHBBLYBAJJ-UHFFFAOYSA-N
SMILES	C1CN(CCN1)C2=CC=CC=C2O
PubChem CID	70530

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	2 / 3
TPSA	35.5 Å²
Synonyms	2-(1-piperazinyl)phenol, o-(1-Piperazinyl)phenol, 1-(2-Hydroxyphenyl)piperazine, 2-(1-Piperazino)phenol, Phenol, 2-(1-piperazinyl)-, 1-(2-Hydroxyphenyl)-piperazine, n-(2-hydroxyphenyl)piperazine, 2-piperazinylphenol, 2-(piperazine-1-yl)phenol, 4-(2-hydroxyphenyl)-piperazine, 1-(2-hydroxy-phenyl)-piperazine

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P363, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(Piperazin-1-yl)phenol?

The CAS Registry Number of 2-(Piperazin-1-yl)phenol is 1011-17-2. It is also known as 2-(1-piperazinyl)phenol, o-(1-Piperazinyl)phenol, 1-(2-Hydroxyphenyl)piperazine.

What is the molecular formula and molecular weight of 2-(Piperazin-1-yl)phenol?

2-(Piperazin-1-yl)phenol has the molecular formula C10H14N2O and a molecular weight of 178.23 g/mol. Its IUPAC name is 2-piperazin-1-ylphenol.

What is 2-(Piperazin-1-yl)phenol used for?

2-(Piperazin-1-yl)phenol is supplied as a characterised reference material related to Vortioxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(Piperazin-1-yl)phenol can I order?

We supply 2-(Piperazin-1-yl)phenol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(Piperazin-1-yl)phenol?

Yes. Every lot of 2-(Piperazin-1-yl)phenol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(Piperazin-1-yl)phenol be shipped internationally?

Yes. 2-(Piperazin-1-yl)phenol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.