2-Pyrimidinemethanamine hydrochloride

Name: 2-Pyrimidinemethanamine hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-035863

About 2-Pyrimidinemethanamine hydrochloride

2-Pyrimidinemethanamine hydrochloride (CAS 372118-67-7) is an impurity of Avanafil offered by Vaqora Chemicals. Formula C5H8ClN3, molecular weight 145.59 g/mol. Alternative names: pyrimidin-2-ylmethanamine hydrochloride and 2-Aminomethylpyrimidine HCl.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Avanafil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Pyrimidinemethanamine hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avanafil

View every impurity, metabolite and intermediate we list for Avanafil.

Avanafil impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Pyrimidinemethanamine hydrochloride
Catalogue No.	VQ-035863
CAS Number	372118-67-7
IUPAC name	pyrimidin-2-ylmethanamine;hydrochloride
Molecular formula	C₅H₈ClN₃
Molecular weight	145.59 g/mol
Exact mass	145.0407
Grade	Reference Standard
HSN code	38229090
InChIKey	RZNKMZKAXJTLQR-UHFFFAOYSA-N
SMILES	C1=CN=C(N=C1)CN.Cl
PubChem CID	17848325

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	51.8 Å²
Synonyms	1-(pyrimidin-2-yl)methanamine hydrochloride (1:1), pyrimidin-2-ylmethanamine hydrochloride, 2-Aminomethylpyrimidine HCl, 2-Aminomethylpyrimidine (hydrochloride), 2-(Aminomethyl)pyrimidine HCl, (pyrimidin-2-yl)methanamine hydrochloride, 2-(Aminomethyl)pyrimidine Hydrochloride, 2-Pyrimidinemethanamine, monohydrochloride, Pyrimidin-2-ylmethanamine HCl, (pyrimidin-2-yl)metha, pyrimidin-2-ylmethanaminehydrochloride, 1-(Pyrimidin-2-yl)methanamine--hydrogen chloride (1/1)

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Pyrimidinemethanamine hydrochloride?

The CAS Registry Number of 2-Pyrimidinemethanamine hydrochloride is 372118-67-7. It is also known as 1-(pyrimidin-2-yl)methanamine hydrochloride (1:1), pyrimidin-2-ylmethanamine hydrochloride, 2-Aminomethylpyrimidine HCl.

What is the molecular formula and molecular weight of 2-Pyrimidinemethanamine hydrochloride?

2-Pyrimidinemethanamine hydrochloride has the molecular formula C5H8ClN3 and a molecular weight of 145.59 g/mol.

What is 2-Pyrimidinemethanamine hydrochloride used for?

2-Pyrimidinemethanamine hydrochloride is supplied as a characterised reference material related to Avanafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Pyrimidinemethanamine hydrochloride can I order?

We supply 2-Pyrimidinemethanamine hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Pyrimidinemethanamine hydrochloride?

Yes. Every lot of 2-Pyrimidinemethanamine hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Pyrimidinemethanamine hydrochloride be shipped internationally?

Yes. 2-Pyrimidinemethanamine hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.